Abstract

This Core integrates and enhances the capabilities of two existing Cores at KUMC: the Electron Microscope Research Laboratory (EMRL) and the Confocal Imaging Facility (CIF), both of which have assisted KUMC investigators for many years. The High Resolution Imaging Core provides cost-effective and time-saving services for the preparation and viewing of samples by confocal and scanning and transmission electron microscopy. Most of the members of this COBRE have steady needs for high resolution microscopy, and this Core has kept pace with advances in technology and equipment. A new super resolution microscope (requested in a separate and pending S10 application to NIGMS) will be housed in space assigned to this COBRE-supported Core and staffed by Core personnel.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Center Core Grants (P30)
Project #
5P30GM122731-02
Application #
9516004
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
2
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of Kansas
Department
Type
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160

  Publications

Kumar, Dhruv; Yalamanchali, Sreeya; New, Jacob et al. (2018) Development and Characterization of an In Vitro Model for Radiation-Induced Fibrosis. Radiat Res 189:326-336
Cork, Gentry K; Thompson, Jeffrey; Slawson, Chad (2018) Real Talk: The Inter-play Between the mTOR, AMPK, and Hexosamine Biosynthetic Pathways in Cell Signaling. Front Endocrinol (Lausanne) 9:522
McCarson, Kenneth E; Winter, Michelle K; Abrahamson, Dale R et al. (2018) Assessing complex movement behaviors in rodent models of neurological disorders. Neurobiol Learn Mem :
Raman, Archana; Parnell, Stephen C; Zhang, Yan et al. (2018) Periostin overexpression in collecting ducts accelerates renal cyst growth and fibrosis in polycystic kidney disease. Am J Physiol Renal Physiol :
Pierce, Angela N; Eller-Smith, Olivia C; Christianson, Julie A (2018) Voluntary wheel running attenuates urinary bladder hypersensitivity and dysfunction following neonatal maternal separation in female mice. Neurourol Urodyn 37:1623-1632
Wang, Huizhen; Luo, Jinping; Carlton, Carol et al. (2017) Sperm-oocyte contact induces outside-in signaling via PYK2 activation. Dev Biol 428:52-62
Pohler, Ky G; Green, Jonathan A; Moley, Laura A et al. (2017) Circulating microRNA as candidates for early embryonic viability in cattle. Mol Reprod Dev 84:731-743
Rogers, Robert S; Tungtur, Sudheer; Tanaka, Tomohiro et al. (2017) Impaired Mitophagy Plays a Role in Denervation of Neuromuscular Junctions in ALS Mice. Front Neurosci 11:473
Trembath, Andrew P; Sharma, Neekun; Raju, Saravanan et al. (2017) A Protective Role for NKG2D-H60a Interaction via Homotypic T Cell Contact in Nonobese Diabetic Autoimmune Diabetes Pathogenesis. Immunohorizons 1:198-212
New, Jacob; Arnold, Levi; Ananth, Megha et al. (2017) Secretory Autophagy in Cancer-Associated Fibroblasts Promotes Head and Neck Cancer Progression and Offers a Novel Therapeutic Target. Cancer Res 77:6679-6691