The Infant Primate Research Laboratory (IPRL) is supported as a Core facility of both the Center on Human Development and Disability (CHDD) and the Washington National Primate Research Center (WaNPRC). For over 30 years, the overall objective of this Core has been to provide a range of technical services, equipment, and facilifies to CHDD Research Affiliates using nonhuman primates in research related to children's health and developmental disabilities. Research projects in past years focused on important topics including fetal alcohol syndrome, pediatric AIDS, and premature birth or low-birth weight. Current projects continue to address important issues such as the developmental consequences of early therapeufic drug exposures, intervenfion strategies for anoxia at birth, and the prevention of premature delivery related to maternal infecfion. These studies are complex and take years to complete. Recent grant awards to CHDD Research Affiliates have indicated that the services and expertise provided by the IPRL are a crifical element for the success of their projects.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Center Core Grants (P30)
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Special Emphasis Panel (ZHD1-MRG-C)
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University of Washington
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Boland, Michael J; Nazor, Kristopher L; Tran, Ha T et al. (2017) Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome. Brain 140:582-598
Klusek, Jessica; LaFauci, Giuseppe; Adayev, Tatyana et al. (2017) Reduced vagal tone in women with the FMR1 premutation is associated with FMR1 mRNA but not depression or anxiety. J Neurodev Disord 9:16
Choi, Won-Seok; Kim, Hyung-Wook; Tronche, François et al. (2017) Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson's disease-like non-motor symptoms without loss of dopamine neurons. Sci Rep 7:44989
Zhou, Vanessa; Munson, Jeffrey A; Greenson, Jessica et al. (2017) An exploratory longitudinal study of social and language outcomes in children with autism in bilingual home environments. Autism :1362361317743251
Pasalich, Dave S; Fleming, Charles B; Oxford, Monica L et al. (2016) Can Parenting Intervention Prevent Cascading Effects From Placement Instability to Insecure Attachment to Externalizing Problems in Maltreated Toddlers? Child Maltreat 21:175-85
Su, Wei; Kang, John; Sopher, Bryce et al. (2016) Recombinant adeno-associated viral (rAAV) vectors mediate efficient gene transduction in cultured neonatal and adult microglia. J Neurochem 136 Suppl 1:49-62
Wheeler, Anne C; Sideris, John; Hagerman, Randi et al. (2016) Developmental profiles of infants with an FMR1 premutation. J Neurodev Disord 8:40
Schneider, A; Johnston, C; Tassone, F et al. (2016) Broad autism spectrum and obsessive-compulsive symptoms in adults with the fragile X premutation. Clin Neuropsychol 30:929-43
Gonçalves, Thaís Fernandez; dos Santos, Jussara Mendonça; Gonçalves, Andressa Pereira et al. (2016) Finding FMR1 mosaicism in Fragile X syndrome. Expert Rev Mol Diagn 16:501-7
Yrigollen, Carolyn M; Pacini, Laura; Nobile, Veronica et al. (2016) Clinical and Molecular Assessment in a Female with Fragile X Syndrome and Tuberous Sclerosis. J Genet Disord Genet Rep 5:

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