This Core, renamed from the Design and Statistical Computing Core to the Data Management and Statistical Analysis (DMSA) Core, has been part of the UNC Mental Retardation Research Center since 1987, and now also includes access to expertise related to the microarray gene expression added to the UNC DDRC in 2003. The overall objectives of the DMSA Core are to enhance the productivity of UNC DDRC investigators and to enhance the quality of their research. We achieve these objectives by collaborating with investigators, providing them with services through every stage of a research project. We participate in writing grant proposals, developing efficient experimental designs, designing data collection instruments, conducting pilot tests, designing and implementing database management systems, supervising execution of the study and collection of data, operating database management systems to clean, store, and retrieve data, performing statistical analyses, writing research papers and reports, and archiving databases. To each phase of the research effort we contribute the unique perspectives and experiences of psychometricians, biostatisticians, professionally trained research database managers, and a support staff of proficient programmers and data managers. Our efforts regarding both traditional data management and analysis and bioinformatics have been integrated into the UNC DDRC. Drs. Burchinal, Gu, Poe, and Zu have been consistent co-authors in publication and Drs. Burchinal, Wright, Gu, Poe, and Neebe have been co-investigators on UNC DDRC projects.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD003110-45
Application #
8380942
Study Section
Special Emphasis Panel (ZHD1-MRG-C)
Project Start
Project End
2014-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
45
Fiscal Year
2012
Total Cost
$529,138
Indirect Cost
$123,188
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Robinson, Ashley N; Roberts, Jane E; Brady, Nancy C et al. (2016) Physiological Correlates of Maternal Responsivity in Mothers of Preschoolers With Fragile X Syndrome. Am J Intellect Dev Disabil 121:111-20
Judson, Matthew C; Wallace, Michael L; Sidorov, Michael S et al. (2016) GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility. Neuron 90:56-69
Klusek, Jessica; McGrath, Sara E; Abbeduto, Leonard et al. (2016) Pragmatic Language Features of Mothers With the FMR1 Premutation Are Associated With the Language Outcomes of Adolescents and Young Adults With Fragile X Syndrome. J Speech Lang Hear Res 59:49-61
Resendez, Shanna L; Jennings, Josh H; Ung, Randall L et al. (2016) Visualization of cortical, subcortical and deep brain neural circuit dynamics during naturalistic mammalian behavior with head-mounted microscopes and chronically implanted lenses. Nat Protoc 11:566-97
Hong, Junpyo; Vicory, Jared; Schulz, Jörn et al. (2016) Non-Euclidean classification of medically imaged objects via s-reps. Med Image Anal 31:37-45
Jha, Shaili C; Meltzer-Brody, Samantha; Steiner, Rachel J et al. (2016) Antenatal depression, treatment with selective serotonin reuptake inhibitors, and neonatal brain structure: A propensity-matched cohort study. Psychiatry Res 253:43-53
Pearson, Brandon L; Simon, Jeremy M; McCoy, Eric S et al. (2016) Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration. Nat Commun 7:11173
Mabb, Angela M; Simon, Jeremy M; King, Ian F et al. (2016) Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms. PLoS One 11:e0156439
Woynaroski, Tiffany; Yoder, Paul; Watson, Linda R (2016) Atypical Cross-Modal Profiles and Longitudinal Associations Between Vocabulary Scores in Initially Minimally Verbal Children With ASD. Autism Res 9:301-10
Kirby, Anne V; Little, Lauren M; Schultz, Beth et al. (2016) Development and Pilot of the Caregiver Strategies Inventory. Am J Occup Ther 70:7004360010p1-6

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