The Rodent Models Core is essential to the success of IDDRC projects that use rodent models for the study of normal and abnormal development and degeneration of the nervous system. The Rodent Models Core provides technical support for the generation and characterization of transgenic, knock-out, and knock-in strains of mice, access to sophisticated shared behavioral equipment, and expertise in the behavioral phenotyping of mouse and rat models of IDD and related disorders. The Rodent Models Core was rated """"""""outstanding"""""""" in the review from 2005, while being in the midst of planning for a major renovation and introduction of entirely new services (i.e., behavioral testing). The Core was highly rated for its leadership (""""""""This application was written with impressive insights into research needs, and great attention to detail'), planning of the new design (""""""""Barrier, non-barrier, and quarantine rooms are now in abundance, with thorough security and thoughtful facility management'), and support for research. However, questions were voiced in two areas: 1) the interim status of the renovation and facility management staffing (the overall summary commented that """"""""a degree of uncertainty remains with the Rodent Models Core, since the person who will manage the core has not yet been hired, and the facility is not yet completed') and 2) the prediction that we would have difficulty hiring a PhD level staff member for the behavioral testing service and the mistaken impression that only two investigators would actually make use of the behavioral facility. Five years later, we believe we have successfully met all of our milestones. The renovation was completed with creation of a dedicated suite for behavioral testing, acquisition of major equipment, and upgrade of infrastructure, transforming the RMC into a barrier facility. All staff, including the facility manager and PhD level psychologist for the Behavioral Testing Suite, were hired, trained, and are now stable members of the Waisman IDDRC core staff. The RMC is now an outstanding resource that is central to the scientific programs of 16 IDDRC investigators.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD003352-48
Application #
8734265
Study Section
Special Emphasis Panel (ZHD1)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
48
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Type
DUNS #
City
Madison
State
WI
Country
United States
Zip Code
53715
Lundwall, Rebecca A; Woodruff, Jason; Tolboe, Steven P (2018) RT Slowing to Valid Cues on a Reflexive Attention Task in Children and Young Adults. Front Psychol 9:1324
Hess, Christi L; Misurelli, Sara M; Litovsky, Ruth Y (2018) Spatial Release From Masking in 2-Year-Olds With Normal Hearing and With Bilateral Cochlear Implants. Trends Hear 22:2331216518775567
Laxman, D J; Greenberg, J S; DaWalt, L S et al. (2018) Medication use by adolescents and adults with fragile X syndrome. J Intellect Disabil Res 62:94-105
Li, James J; Lansford, Jennifer E (2018) A smartphone-based ecological momentary assessment of parental behavioral consistency: Associations with parental stress and child ADHD symptoms. Dev Psychol 54:1086-1098
Lundwall, Rebecca A; Sgro, Jordan F; Fanger, Julia (2018) Response time scores on a reflexive attention task predict a child's inattention score from a parent report. PLoS One 13:e0190724
Morrison, Ryann A; Martinez, Jonathan I; Hilton, Emily C et al. (2018) The influence of parents and schools on developmental trajectories of antisocial behaviors in Caucasian and African American youths. Dev Psychopathol :1-13
Patzlaff, Natalie E; Shen, Minjie; Zhao, Xinyu (2018) Regulation of Adult Neurogenesis by the Fragile X Family of RNA Binding Proteins. Brain Plast 3:205-223
Vijayan, Murali; Kumar, Subodh; Yin, Xiangling et al. (2018) Identification of novel circulatory microRNA signatures linked to patients with ischemic stroke. Hum Mol Genet 27:2318-2329
Plate, Rista C; Fulvio, Jacqueline M; Shutts, Kristin et al. (2018) Probability Learning: Changes in Behavior Across Time and Development. Child Dev 89:205-218
Hartley, Sigan L; Papp, Lauren M; Bolt, Daniel (2018) Spillover of Marital Interactions and Parenting Stress in Families of Children With Autism Spectrum Disorder. J Clin Child Adolesc Psychol 47:S88-S99

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