Abstract

The purpose of the Laboratory Animal Core facility is to provide selected services and animals (rats and mice) of high quality to eligible projects of the P30 Center at a reasonable price. The facility breeds and maintains a colony of Sprague-Dawley rats as required by investigators. The Core provides Center investigators with rats and mice of specific ages and sexes, and pregnant females of known gestational age. In addition, the facility provides various technical services and routine surgical procedures as needed by the investigators. The Laboratory Animal Core is a specific pathogen-free facility and strives to provide the healthiest animals possible. The personnel of the Laboratory Animal Core are available as well to teach members of the P30 Center animal handling and surgical procedures according to procedures approved by the University's Committee on Animal Use.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD018258-15
Application #
6108396
Study Section
Project Start
1998-04-01
Project End
2000-03-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
15
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Type
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Mahoney, Megan M; Rossi, Brooke V; Hagenauer, Megan H et al. (2011) Characterization of the estrous cycle in Octodon degus. Biol Reprod 84:664-71
Tsuneta, Taeko; Loch-Caruso, Rita; Quensen 3rd, John F et al. (2008) Stimulatory effects of a microbially dechlorinated polychlorinated biphenyl (PCB) mixture on rat uterine contraction in vitro. Environ Res 107:185-93
Caruso, Rita Loch; Upham, Brad L; Harris, Craig et al. (2005) Biphasic lindane-induced oxidation of glutathione and inhibition of gap junctions in myometrial cells. Toxicol Sci 86:417-26
Loch-Caruso, Rita; Upham, Brad L; Harris, Craig et al. (2005) Divergent roles for glutathione in lindane-induced acute and delayed-onset inhibition of rat myometrial gap junctions. Toxicol Sci 85:694-702
Billings, Heather J; Viguie, Catherine; Karsch, Fred J et al. (2002) Temporal requirements of thyroid hormones for seasonal changes in LH secretion. Endocrinology 143:2618-25
Bae, J; Mousa, M A; Quensen 3rd, J F et al. (2001) Stimulation of contraction of pregnant rat uterus in vitro by non-dechlorinated and microbially dechlorinated mixtures of polychlorinated biphenyls. Environ Health Perspect 109:275-82
West, C; Foster, D L; Evans, N P et al. (2001) Intra-follicular activin availability is altered in prenatally-androgenized lambs. Mol Cell Endocrinol 185:51-9
Williams, C Y; Harris, T G; Battaglia, D F et al. (2001) Endotoxin inhibits pituitary responsiveness to gonadotropin-releasing hormone. Endocrinology 142:1915-22
Viguie, C; Jansen, H T; Glass, J D et al. (2001) Potential for polysialylated form of neural cell adhesion molecule-mediated neuroplasticity within the gonadotropin-releasing hormone neurosecretory system of the ewe. Endocrinology 142:1317-24
Olson, K K; Anderson, L E; Wiltbank, M C et al. (2001) Actions of prostaglandin F2alpha and prolactin on intercellular adhesion molecule-1 expression and monocyte/macrophage accumulation in the rat corpus luteum. Biol Reprod 64:890-7

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