The objective of the Human Clinical Phenotyping Core (HCP) is to promote excellence in human phenotyping, with a central mission to facilitate research on intellectual and developmental disabilities (IDD) by a diverse interdisciplinary team of investigators across the Einstein campus. The Core maintains a centralized easily searchable de-identified database of participants for access by Einstein investigators that includes information about data collection from the Neurogenomics and Translational Neuroimaging Cores, and provides continuity to HCP-enrolled participants as they traverse the different Cores and engage in research projects. The HCP is essential to the mission of the RFK-IDDRC to advance diagnosis, prevention, and treatment of children with developmental disabilities, and is positioned to serve as the central hub for a variety of RFK-IDDRC investigators for whom comprehensive phenotyping is key to understanding the implications of their work. It increases access to the populations of interest, increases the cost-effectiveness of research endeavors in well-characterized clinical populations, and facilitates collaboration among researchers with varied and complementary skill-sets and backgrounds.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD071593-04
Application #
8734921
Study Section
Special Emphasis Panel (ZHD1-DSR-Y)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
4
Fiscal Year
2014
Total Cost
$177,000
Indirect Cost
$71,013
Name
Albert Einstein College of Medicine
Department
Type
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461
Murphy, Jeremy W; Foxe, John J; Molholm, Sophie (2016) Neuro-oscillatory mechanisms of intersensory selective attention and task switching in school-aged children, adolescents and young adults. Dev Sci 19:469-87
Sikora, Jakub; Leddy, Jennifer; Gulinello, Maria et al. (2016) X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities. Dis Model Mech 9:13-23
Morie, Kristen P; De Sanctis, Pierfilippo; Garavan, Hugh et al. (2016) Regulating task-monitoring systems in response to variable reward contingencies and outcomes in cocaine addicts. Psychopharmacology (Berl) 233:1105-18
Dimitriadi, Maria; Derdowski, Aaron; Kalloo, Geetika et al. (2016) Decreased function of survival motor neuron protein impairs endocytic pathways. Proc Natl Acad Sci U S A 113:E4377-86
Uppal, Neha; Foxe, John J; Butler, John S et al. (2016) The neural dynamics of somatosensory processing and adaptation across childhood: a high-density electrical mapping study. J Neurophysiol 115:1605-19
Andrade, G N; Butler, J S; Peters, G A et al. (2016) Atypical visual and somatosensory adaptation in schizophrenia-spectrum disorders. Transl Psychiatry 6:e804
Arteaga-Bracho, Eduardo E; Gulinello, Maria; Winchester, Michael L et al. (2016) Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease. Neurobiol Dis 96:144-155
Nebel, Rebecca A; Zhao, Dejian; Pedrosa, Erika et al. (2016) Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks. PLoS One 11:e0148039
Molero, Aldrin E; Arteaga-Bracho, Eduardo E; Chen, Christopher H et al. (2016) Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease. Proc Natl Acad Sci U S A 113:5736-41
Díaz-Balzac, Carlos A; Rahman, Maisha; Lázaro-Peña, María I et al. (2016) Muscle- and Skin-Derived Cues Jointly Orchestrate Patterning of Somatosensory Dendrites. Curr Biol 26:2379-87

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