This application proposes the renewal for 2014-2019 of the Center for AIDS Intervention Research (CAIR) at the Medical College of Wisconsin as an HIV behavioral research Center. CAIR's thematic mission is the conceptualization, conduct, and rigorous evaluation of interventions to prevent HIV infection in communities most vulnerable to the disease;the development of interventions to improve health outcomes among persons living with the disease;and the rapid dissemination of research findings to both the scientific community and public health service provides. The Center's Core structure supports the efforts of an interdisciplinary team of HIV prevention investigators, and CAIR has been highly productive and a strong regional, national, and international resource in the areas of research, training, and service to the scientific and public health communities. CAIR Investigators have made distinguished scientific contributions in the development of HIV prevention interventions for high-incidence populations in the United States, Eastern Europe, and other regions of the world;have advanced the field's scientific knowledge of how to transfer scientific advances to benefit service providers nationally and internationally;and have undertaken vigorous lines of behavioral and social science, methodological, and cost-effectiveness research applied to HIV prevention. CAIR's specific aims during the renewal period are: 1) the development of behavioral, social, and structural interventions that will lead to wide scale public health implementation of recently-emerging biomedical HIV prevention strategies;2) establishing the effectiveness of multi-level HIV prevention interventions that combine potent behavioral, social, structural, and biomedical interventions to achieve greatest public health impact in reducing HIV incidence;3) reducing HIV-related health disparities;and 4) serving as a resource that rapidly transforms scientific advances into sustainable public health practice. To support continued excellence in these areas, we propose a structure that brings together interdisciplinary teams and provides resources from the following Cores: Administration Core (Center strategic planning and oversight);Developmental Core (preliminary studies, internal peer review, Center conferences and professional development);Qualitative Core (qualitative and social science support);Quantitative Core (central data management, analysis, and biostatistical consultation);Intervention and Dissemination Core (intervention trial support and technology exchange initiatives);International Core (facilitating international initiatives);and Impact Science Core HIV prevention economic, modeling, and impact analyses). Center Cores synergistically interact, provide added value, and support achievement of CAIR's research aims.

Public Health Relevance

REVELANCE: With a wide array of new prevention strategies now available, the field is at a pivotal point where, for the first time, it is possible to envision how to end th HIV epidemic. During its Center renewal period, CAIR's research will emphasize integrated prevention approaches that combine the most potent behavioral, social, structural, and biomedical modalities to achieve high public health impact by reducing HIV incidence within communities most affected by the disease.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Center Core Grants (P30)
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Special Emphasis Panel (ZMH1-ERB-M (02))
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Gordon, Christopher M
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Medical College of Wisconsin
Schools of Medicine
United States
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Quinn, Katherine; Dickson-Gomez, Julia (2016) Homonegativity, Religiosity, and the Intersecting Identities of Young Black Men Who Have Sex with Men. AIDS Behav 20:51-64
Quinn, Katherine; Voisin, Dexter R; Bouris, Alida et al. (2016) Multiple Dimensions of Stigma and Health Related Factors Among Young Black Men Who Have Sex with Men. AIDS Behav :
Kuznetsova, Anna V; Meylakhs, Anastasia Y; Amirkhanian, Yuri A et al. (2016) Barriers and Facilitators of HIV Care Engagement: Results of a Qualitative Study in St. Petersburg, Russia. AIDS Behav 20:2433-43
Glasman, Laura R; Dickson-Gomez, Julia; Lechuga, Julia et al. (2016) Using Peer-Referral Chains with Incentives to Promote HIV Testing and Identify Undiagnosed HIV Infections Among Crack Users in San Salvador. AIDS Behav 20:1236-43
Mitchell, Jason W; Sophus, Amber I; Petroll, Andrew E (2016) HIV-Negative Partnered Men's Willingness to Use Non-Occupational Post-Exposure Prophylaxis and Associated Factors in a U.S. Sample of HIV-Negative and HIV-Discordant Male Couples. LGBT Health 3:146-52
Quinn, Katherine G; Kelly, Jeffrey A; DiFranceisco, Wayne J et al. (2016) The Health and Sociocultural Correlates of AIDS Genocidal Beliefs and Medical Mistrust Among African American MSM. AIDS Behav :
McGarrity, Larissa A; Senn, Theresa E; Walsh, Jennifer L et al. (2016) Psychological Distress Moderates the Intention-Behavior Association for Sexual Partner Concurrency Among Adults. AIDS Behav :
Kelly, Jeffrey A; St Lawrence, Janet S; Tarima, Sergey S et al. (2016) Correlates of Sexual HIV Risk Among African American Men Who Have Sex With Men. Am J Public Health 106:96-102
Mitchell, Jason W (2016) Differences in Relationship Characteristics Between HIV-Negative Male Couples Who Used and Did Not Use Substances with Sex. AIDS Behav 20:667-78
Nydegger, Liesl A; DiFranceisco, Wayne; Quinn, Katherine et al. (2016) Gender Norms and Age-Disparate Sexual Relationships as Predictors of Intimate Partner Violence, Sexual Violence, and Risky Sex among Adolescent Gang Members. J Urban Health :

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