The HIV epidemic remains one of the foremost health challenges of the modern era. It requires a response that is multidisciplinary, coordinated, and scientifically sound. This renewal application for the UCSF Center for AIDS Prevention Studies (CAPS) is organized as a five-year strategic plan to develop research focused on three long-term goals: preventing new HIV infections, using behavioral approaches to improve health outcomes among HIV-infected people, and reducing disparities. The Center will foster innovative and multidisciplinary HIV research, enhance the quality and relevance of CAPS science, train a new generation of HIV investigators, and assist implementing partners through core support to a diverse portfolio of projects funded by contracts, grants, and cooperative agreements awarded directly to investigators. We are requesting funding for the next five years to support six cores essential to our work:1) The Administrative Core to provide leadership to CAPS scientists, stimulate innovation in research, provide organizational management, and oversee monitoring and evaluation of the Center;2) The Developmental Core to mentor the next generation of HIV scientists, provide pilot funds for innovative projects, and conduct peer review to ensure scientific excellence and relevance;3) The Methods Core to provide training and consultation in research design and state-of-the art data collection, management, and analysis methods;4) The Policy &Ethics Core to ensure that CAPS research meets the highest ethical standards and is communicated appropriately to policy makers, and to support policy and ethics research;5) The Technology and Information Exchange (Domestic Response) Core to disseminate science to community, bring community expertise to scientists, and support community-collaborative research;and 6) The Global Response Core to facilitate international collaborative research, support systematic scientific reviews, and serve as a resource to global implementing partners.

Public Health Relevance

The HIV epidemic is one of the primary public health challenges of modern times. An effective response requires expertise from diverse scientific disciplines, including the social, behavioral, and policy sciences. CAPS serves as an academic hub, providing support and training to scientists conducting research to prevent HIV transmission, improve health outcomes for people living with HIV, and reduce disparities.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH062246-12
Application #
8325001
Study Section
Special Emphasis Panel (ZMH1-ERB-M (03))
Program Officer
Gordon, Christopher M
Project Start
2001-09-24
Project End
2016-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
12
Fiscal Year
2012
Total Cost
$1,745,132
Indirect Cost
$338,253
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Saberi, Parya; Ming, Kristin; Dawson-Rose, Carol (2018) What does it mean to be youth-friendly? Results from qualitative interviews with health care providers and clinic staff serving youth and young adults living with HIV. Adolesc Health Med Ther 9:65-75
Sylla, Laurie; Evans, David; Taylor, Jeff et al. (2018) If We Build It, Will They Come? Perceptions of HIV Cure-Related Research by People Living with HIV in Four U.S. Cities: A Qualitative Focus Group Study. AIDS Res Hum Retroviruses 34:56-66
Leidich, Aimee; Achiro, Lillian; Kwena, Zachary A et al. (2018) Methods for sampling geographically mobile female traders in an East African market setting. PLoS One 13:e0190395
Ssewamala, Fred M; Wang, Julia Shu-Huah; Neilands, Torsten B et al. (2018) Cost-Effectiveness of a Savings-Led Economic Empowerment Intervention for AIDS-Affected Adolescents in Uganda: Implications for Scale-up in Low-Resource Communities. J Adolesc Health 62:S29-S36
Hojilla, J Carlo; Vlahov, David; Crouch, Pierre-Cedric et al. (2018) HIV Pre-exposure Prophylaxis (PrEP) Uptake and Retention Among Men Who Have Sex with Men in a Community-Based Sexual Health Clinic. AIDS Behav 22:1096-1099
Arnold, Emily A; Sterrett-Hong, Emma; Jonas, Adam et al. (2018) Social networks and social support among ball-attending African American men who have sex with men and transgender women are associated with HIV-related outcomes. Glob Public Health 13:144-158
AIDS-defining Cancer Project Working Group of IeDEA, COHERE in EuroCoord (2018) Non-Hodgkin lymphoma risk in adults living with HIV across five continents. AIDS 32:2777-2786
Flentje, Annesa; Kober, Kord M; Carrico, Adam W et al. (2018) Minority stress and leukocyte gene expression in sexual minority men living with treated HIV infection. Brain Behav Immun 70:335-345
Rodriquez, Erik J; Livaudais-Toman, Jennifer; Gregorich, Steven E et al. (2018) Relationships between allostatic load, unhealthy behaviors, and depressive disorder in U.S. adults, 2005-2012 NHANES. Prev Med 110:9-15
Elion, Richard A; Althoff, Keri N; Zhang, Jinbing et al. (2018) Recent Abacavir Use Increases Risk of Type 1 and Type 2 Myocardial Infarctions Among Adults With HIV. J Acquir Immune Defic Syndr 78:62-72

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