Abstract

Dynamic Individualized Prediction of Depression Onset Project Dr. Thompson will lead the """"""""Dynamic Individualized Prediction of Depression Onset Project"""""""". Working closely with Dr. Anderson, Dr. Thompson will develop a Prognostic Bayesian Network (PBN) methodology for applications to preventive outcomes in late life depression. He will implement these methods on existing and ongoing Center-affiliated studies. Dr. Thompson will also develop a freely-available user-friendly software package implementing these methods aimed at late-life depression researchers for use in data analysis and in designing new research studies. He will take the lead in publishing peer-reviewed articles and giving conference talks to publicize this research to a broader audience. Finally, he will work closely with Dr. Anderson in co-directing a graduate student researcher.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH090333-02
Application #
8377371
Study Section
Special Emphasis Panel (ZMH1-ERB-F)
Project Start
Project End
Budget Start
2012-05-01
Budget End
2013-04-30
Support Year
2
Fiscal Year
2012
Total Cost
$80,478
Indirect Cost
$19,748

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Wei, Wenjing; Karim, Helmet T; Lin, Chemin et al. (2018) Trajectories in Cerebral Blood Flow Following Antidepressant Treatment in Late-Life Depression: Support for the Vascular Depression Hypothesis. J Clin Psychiatry 79:
Karim, Helmet T; Wang, Maxwell; Andreescu, Carmen et al. (2018) Acute trajectories of neural activation predict remission to pharmacotherapy in late-life depression. Neuroimage Clin 19:831-839
Rodakowski, Juleen; Reynolds 3rd, Charles F; Lopez, Oscar L et al. (2018) Developing a Non-Pharmacological Intervention for Individuals With Mild Cognitive Impairment. J Appl Gerontol 37:665-676
Miller, Rachel G; Anderson, Stewart J; Costacou, Tina et al. (2018) Hemoglobin A1c Level and Cardiovascular Disease Incidence in Persons With Type 1 Diabetes: An Application of Joint Modeling of Longitudinal and Time-to-Event Data in the Pittsburgh Epidemiology of Diabetes Complications Study. Am J Epidemiol 187:1520-1529
Gebara, Marie Anne; DiNapoli, Elizabeth A; Kasckow, John et al. (2018) Specific depressive symptoms predict remission to aripiprazole augmentation in late-life treatment resistant depression. Int J Geriatr Psychiatry 33:e330-e335
Okereke, Olivia I; Reynolds 3rd, Charles F; Mischoulon, David et al. (2018) The VITamin D and OmegA-3 TriaL-Depression Endpoint Prevention (VITAL-DEP): Rationale and design of a large-scale ancillary study evaluating vitamin D and marine omega-3 fatty acid supplements for prevention of late-life depression. Contemp Clin Trials 68:133-145
Gebara, Marie Anne; Kasckow, John; Smagula, Stephen F et al. (2018) The role of late life depressive symptoms on the trajectories of insomnia symptoms during antidepressant treatment. J Psychiatr Res 96:162-166
Cohen, Alex; Dias, Amit; Azariah, Fredric et al. (2018) Aging and well-being in Goa, India: a qualitative study. Aging Ment Health 22:168-174
Chen, Jie; Bloodworth, Robin; Novak, Priscilla et al. (2018) Reducing Preventable Hospitalization and Disparity: Association With Local Health Department Mental Health Promotion Activities. Am J Prev Med 54:103-112
Smagula, Stephen F; Karim, Helmet T; Lenze, Eric J et al. (2017) Gray matter regions statistically mediating the cross-sectional association of eotaxin and set-shifting among older adults with major depressive disorder. Int J Geriatr Psychiatry 32:1226-1232

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