Depressive symptoms are common in seniors receiving in-home and community-based services. In seniors receiving home-delivered meals, 12% reported clinically significant depression (PHQ >9).(177) In seniors receiving home health nursing, 13.5% met criteria for major depression.(178) The 1 -year incidence of major depression in homebound elders was 3%, and the 1-year incidence for minor depression 7%. (179) Thus, the population of seniors receiving aging services is at high risk for depression and an appropriate target for selective and indicated prevention. Prevention is likely to be highly effective in these seniors, who share many of the depression risk factors identified in epidemiologic research (functional impairments, two or more chronic illnesses, low educational level, and living without a partner, which in one Dutch study identified the 8-10% of the senior population at highest risk for depression).(180-181) Interventions targeting this population could reduce the incidence of depression by one-third to one-half, generating large health gains efficiently, with numbers-needed-to-treat as low as 3-5. (182)

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH090333-03
Application #
8465285
Study Section
Special Emphasis Panel (ZMH1-ERB-F)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
3
Fiscal Year
2013
Total Cost
$121,553
Indirect Cost
$58,574
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Monin, Joan K; Schulz, Richard; Feeney, Brooke C (2015) Compassionate Love in Individuals With Alzheimer's Disease and Their Spousal Caregivers: Associations With Caregivers' Psychological Health. Gerontologist 55:981-9
Skidmore, Elizabeth R; Dawson, Deirdre R; Butters, Meryl A et al. (2015) Strategy Training Shows Promise for Addressing Disability in the First 6 Months After Stroke. Neurorehabil Neural Repair 29:668-76
Richard-Devantoy, St├ęphane; Szanto, Katalin; Butters, Meryl A et al. (2015) Cognitive inhibition in older high-lethality suicide attempters. Int J Geriatr Psychiatry 30:274-83
Schenker, Yael; Dew, Mary Amanda; Reynolds, Charles F et al. (2015) Development of a post-intensive care unit storytelling intervention for surrogates involved in decisions to limit life-sustaining treatment. Palliat Support Care 13:451-63
Gildengers, Ariel G; Butters, Meryl A; Aizenstein, Howard J et al. (2015) Longer lithium exposure is associated with better white matter integrity in older adults with bipolar disorder. Bipolar Disord 17:248-56
Jimenez, Daniel E; Begley, Amy; Bartels, Stephen J et al. (2015) Improving health-related quality of life in older African American and non-Latino White patients. Am J Geriatr Psychiatry 23:548-58
Rodakowski, Juleen; Skidmore, Elizabeth R; Reynolds 3rd, Charles F et al. (2014) Can performance on daily activities discriminate between older adults with normal cognitive function and those with mild cognitive impairment? J Am Geriatr Soc 62:1347-52
Diniz, Breno Satler; Reynolds 3rd, Charles F; Begley, Amy et al. (2014) Brain-derived neurotrophic factor levels in late-life depression and comorbid mild cognitive impairment: a longitudinal study. J Psychiatr Res 49:96-101
Spira, Adam P; Kaufmann, Christopher N; Kasper, Judith D et al. (2014) Association between insomnia symptoms and functional status in U.S. older adults. J Gerontol B Psychol Sci Soc Sci 69 Suppl 1:S35-41
Koenig, Aaron M; Butters, Meryl A; Begley, Amy et al. (2014) Response to antidepressant medications in late-life depression across the spectrum of cognitive functioning. J Clin Psychiatry 75:e100-7

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