Dynamic Individualized Prediction of Depression Onset Project Dr. Thompson will lead the "Dynamic Individualized Prediction of Depression Onset Project". Working closely with Dr. Anderson, Dr. Thompson will develop a Prognostic Bayesian Network (PBN) methodology for applications to preventive outcomes in late life depression. He will implement these methods on existing and ongoing Center-affiliated studies. Dr. Thompson will also develop a freely-available user-friendly software package implementing these methods aimed at late-life depression researchers for use in data analysis and in designing new research studies. He will take the lead in publishing peer-reviewed articles and giving conference talks to publicize this research to a broader audience. Finally, he will work closely with Dr. Anderson in co-directing a graduate student researcher.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH090333-03
Application #
8465288
Study Section
Special Emphasis Panel (ZMH1-ERB-F)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
3
Fiscal Year
2013
Total Cost
$71,981
Indirect Cost
$26,024
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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Diniz, Breno Satler; Reynolds 3rd, Charles F; Begley, Amy et al. (2014) Brain-derived neurotrophic factor levels in late-life depression and comorbid mild cognitive impairment: a longitudinal study. J Psychiatr Res 49:96-101
Spira, Adam P; Kaufmann, Christopher N; Kasper, Judith D et al. (2014) Association between insomnia symptoms and functional status in U.S. older adults. J Gerontol B Psychol Sci Soc Sci 69 Suppl 1:S35-41
Koenig, Aaron M; Butters, Meryl A; Begley, Amy et al. (2014) Response to antidepressant medications in late-life depression across the spectrum of cognitive functioning. J Clin Psychiatry 75:e100-7

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