OVERVIEW The mission of the University of Washington Center for Research on Management of Sleep Disturbances (UW-CRMSD) is to improve health, well being, and quality of life through the enhancement of sleep quality across the lifespan. Sleep disturbances are common, serious, costly and treatable. Over 70 million people In the U.S. have some type of sleep disturbance and many are unaware that they have a problem.''Sleep disturbances are associated with particular sleep disorders (e.g. insomnia, sleep disordered breathing, restless legs syndrome), are often co-morbid with acute and chronic illness states (e.g. arthritis, neurologic disorders, depression) or arise during developmental transitions (e.g. adolescence, menopause, retirement), and are sometimes self-imposed due to lifestyle choices, such as work or caregiving demands. Regardless of etiology, sleep disturbances most often manifest as disrupted or fragmented sleep or as an inadequate amount of sleep. Untreated sleep disturbances pose significant daytime consequences and place individuals of all ages at considerable risk for adverse health outcomes. Children and the elderly are particularly vulnerable to adverse health outcomes from unrecognized and untreated sleep disturbances. Fig, 1 summarizes a conceptual framework for the relationship between sleep disturbances and health outcomes that can occur at any stage of the human lifespan. The UW-CRMSD will address the multi-factorial (e.g., genetics, environment, age/development) nature of sleep disturbances as well as support the development of interventions to improve sleep quality that take Into account important contributing factors such as age, developmental transitions, and chronic illness (Fig. 1).

National Institute of Health (NIH)
National Institute of Nursing Research (NINR)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZNR1-REV-M)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Washington
United States
Zip Code
Tang, Hsin-Yi; Vitiello, Michael V; Perlis, Michael et al. (2014) A pilot study of audio-visual stimulation as a self-care treatment for insomnia in adults with insomnia and chronic pain. Appl Psychophysiol Biofeedback 39:219-25
Barclay, Nicola L; Watson, Nathaniel F; Buchwald, Dedra et al. (2014) Moderation of genetic and environmental influences on diurnal preference by age in adult twins. Chronobiol Int 31:222-31
Ward, Teresa M; Sonney, Jennifer; Ringold, Sarah et al. (2014) Sleep disturbances and behavior problems in children with and without arthritis. J Pediatr Nurs 29:321-8
Watson, Nathaniel F; Harden, Kathryn Paige; Buchwald, Dedra et al. (2014) Sleep duration and depressive symptoms: a gene-environment interaction. Sleep 37:351-8
Thomas, Karen A; Burr, Robert L; Spieker, Susan et al. (2014) Mother-infant circadian rhythm: development of individual patterns and dyadic synchrony. Early Hum Dev 90:885-90
Crosta, Quinn R; Ward, Teresa M; Walker, Amy J et al. (2014) A review of pain measures for hospitalized children with cognitive impairment. J Spec Pediatr Nurs 19:109-18
Landis, Carol A (2014) Is melatonin the next "new" therapy to improve sleep and reduce pain? Sleep 37:1405-6
Taibi, Diana M; Landis, Carol A; Vitiello, Michael V (2013) Concordance of polysomnographic and actigraphic measurement of sleep and wake in older women with insomnia. J Clin Sleep Med 9:217-25
Ringold, Sarah; Ward, Teresa M; Wallace, Carol A (2013) Disease activity and fatigue in juvenile idiopathic arthritis. Arthritis Care Res (Hoboken) 65:391-7
Liu, Pei-Ching; Kieckhefer, Gail M; Gau, Bih-Shya (2013) A systematic review of the association between obesity and asthma in children. J Adv Nurs 69:1446-65

Showing the most recent 10 out of 18 publications