The P30 Center of Excellence for Biobehavioral Approaches to Symptom Management (CEBASM) builds on our successful P20 Exploratory Center for Biobehavioral Clinical Research (CBCR, P20 NR008988, 2004- 2009).The CEBASM will take advantage of the synergy developed via the CBCR related to symptom management and biobehavioral outcomes as well as resources garnered and systems developed for that Center and expand them to advanced application of biobehavioral models, methods, and analyses aimed at understanding biobehavioral mechanisms, interventions, and outcomes related to symptom management with a focus on fatigue.
The specific aims of the proposed P30 Center of Excellence are to: 1) expand biobehavioral research capacity for scientists conducting nursing research by centralizing research resources and infrastructure for biobehavioral clinical research focused on symptom management;2) advance biobehavioral approaches for symptom management, including fatigue and its associated symptoms, in diverse populations;3) facilitate the development and expansion of biobehavioral programs of independent, investigator-initiated biobehavioral research that have a common theme of fatigue;and 4) establish a mature environment of sustainable biobehavioral research in symptom management that is clinically focused and interdisciplinary in nature. The Center will enact its aims through the work of its cores for Biobehavioral Science, Biobehavioral Measurement, and Data Services and Analysis and through the implementation of five funded research projects studying fatigue in women with fibromyalgia, women with breast cancer, pregnant women, women with cardiometabolic risk, and adolescents and young adults with sickle cell disease. The Center will guide the development, integration, synthesis, and dissemination of current and evolving biobehavioral scientific domains, including advances in measurement and data analysis of fatigue and associated phenomena and will provide consultation to scientists in the larger biobehavioral research community.

Public Health Relevance

Fatigue is a highly prevalent and distressing symptom across populations. The Center of Excellence for Biobehavioral Approaches to Symptom Management (CEBASM) use state-of-the-science as well as emerging methods, measures, and technologies to expand our understanding of fatigue and its influence on health outcomes.

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Center Core Grants (P30)
Project #
5P30NR011403-05
Application #
8470487
Study Section
Special Emphasis Panel (ZNR1-REV-M (01))
Program Officer
Mccloskey, Donna J
Project Start
2009-08-10
Project End
2014-05-31
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
5
Fiscal Year
2013
Total Cost
$376,515
Indirect Cost
$122,344
Name
Virginia Commonwealth University
Department
Other Health Professions
Type
Schools of Nursing
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298
Grap, Mary Jo; Burk, Ruth Srednicki; Lucas, Valentina et al. (2015) Use of high frequency ultrasound to detect changes in skin integrity: An image evaluation validation procedure. Intensive Crit Care Nurs 31:141-7
Montpetit, Alison J; Alhareeri, Areej A; Montpetit, Marty et al. (2014) Telomere length: a review of methods for measurement. Nurs Res 63:289-99
Sturgill, Jamie; McGee, Elizabeth; Menzies, Victoria (2014) Unique cytokine signature in the plasma of patients with fibromyalgia. J Immunol Res 2014:938576
Starkweather, Angela R; Sherwood, Paula; Lyon, Debra E et al. (2014) Depressive symptoms and cytokine levels in Serum and Tumor Tissue in patients with an Astrocytoma: a pilot study. BMC Res Notes 7:423
Macpherson, Catherine Fiona; Linder, Lauri A; Ameringer, Suzanne et al. (2014) Feasibility and acceptability of an iPad application to explore symptom clusters in adolescents and young adults with cancer. Pediatr Blood Cancer 61:1996-2003
Kinser, Patricia Anne; Elswick, R K; Kornstein, Susan (2014) Potential long-term effects of a mind-body intervention for women with major depressive disorder: sustained mental health improvements with a pilot yoga intervention. Arch Psychiatr Nurs 28:377-83
Menzies, Victoria; Lyon, Debra E; Elswick Jr, R K et al. (2014) Effects of guided imagery on biobehavioral factors in women with fibromyalgia. J Behav Med 37:70-80
Ameringer, Suzanne; Elswick Jr, R K; Smith, Wally (2014) Fatigue in adolescents and young adults with sickle cell disease: biological and behavioral correlates and health-related quality of life. J Pediatr Oncol Nurs 31:6-17
Lyon, Debra; McCain, Nancy; Elswick, R K et al. (2014) Biobehavioral examination of fatigue across populations: report from a P30 Center of Excellence. Nurs Outlook 62:322-31
Starkweather, Angela R; Lyon, Debra E; Schubert, Christine M (2013) Pain and inflammation in women with early-stage breast cancer prior to induction of chemotherapy. Biol Res Nurs 15:234-41

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