Sleep is a fundamental physiologic function that plays a ubiquitous role in health and illness. The Sleep Measurement Core will provide essential expertise, service and the tools required to undertake symptom science research that focuses upon sleep. Sleep measurement tools range from self report questionnaires to actigraphy to quantification of electroencephalographic (EEG) recordings of brain waveforms via polysomnography (PSG) from which to interpret sleep architecture. The Core specific aims are: (1) expand the number of research investigators involved in high quality, innovative interdisciplinary biobehavioral sleep research;(2) consult with and provide technical support to investigators desiring to integrate sleep measurement within their current program of research;and (3) develop and maintain a full array of sleep measurement tools and analysis resources in partnership with existing sleep measurement opportunities at Johns Hopkins University. This Core and Center seek to address the relationship between sleep disturbance and symptom severity, an important aspect of sleep-disease interactions that has been largely neglected. A particularly novel strength of the proposed Core is the integration of symptom modeling in the rat which permits rigorous exploration of underlying mechanisms and enhances the likelihood for translational discovery when combined with the Core's human sleep research capacity and expertise. The Core faculty are very broad in expertise, enhancing the potential for collaboration, an important factor in building a sustainable Center infrastructure.

Public Health Relevance

More than 25% of the adult population of the U.S. suffers from sleep disturbances now known to contribute to disability, disease and death. The Sleep Measurement Core will provide expertise, service, and the tools needed to develop skill in the conduct of sleep research. It is important to increase the number of sleep investigators to develop an understanding of the caused underlying the role of sleep in health and illness.

Agency
National Institute of Health (NIH)
Type
Center Core Grants (P30)
Project #
5P30NR014131-03
Application #
8687528
Study Section
Special Emphasis Panel (ZNR1)
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
City
Baltimore
State
MD
Country
United States
Zip Code
Finan, Patrick H; Buenaver, Luis F; Coryell, Virginia T et al. (2014) Cognitive-Behavioral Therapy for Comorbid Insomnia and Chronic Pain. Sleep Med Clin 9:261-274
Finan, Patrick H; Zautra, Alex J (2013) Rheumatoid arthritis: stress affects rheumatoid arthritis, but via what mechanisms? Nat Rev Rheumatol 9:569-70