This Core will provide training, consultation, and state of the art equipment necessary for confocal and multiphoton imaging in support of NINDS-fund and other neuroscientists at UNC-Chapel Hill. Core 2 .was established with, and is funded jointly by, the Carolina Institute for Developmental Disabilities (CIDD). The CIDD supports interdisciplinary clinical. and basic investigations into neurodevelopmental disorders and autism.. In addition to providing access. to .high resolution imaging technologies, Core 2 also implements new imaging technologies, particularly related to real time imaging of neurodevelopment, and provides? training to support the imaging needs of NINDS-funded and other neuroscientists at UNC. Core expenses are partially defrayed by a university approved recharge system.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
2P30NS045892-11
Application #
8791162
Study Section
Special Emphasis Panel (ZNS1)
Project Start
Project End
Budget Start
2014-02-01
Budget End
2014-11-30
Support Year
11
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Sinnett, Sarah E; Hector, Ralph D; Gadalla, Kamal K E et al. (2017) Improved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery. Mol Ther Methods Clin Dev 5:106-115
McHenry, Jenna A; Otis, James M; Rossi, Mark A et al. (2017) Hormonal gain control of a medial preoptic area social reward circuit. Nat Neurosci 20:449-458
Decot, Heather K; Namboodiri, Vijay M K; Gao, Wei et al. (2017) Coordination of Brain-Wide Activity Dynamics by Dopaminergic Neurons. Neuropsychopharmacology 42:615-627
Hirsch, Matthew L; Conatser, Laura M; Smith, Sara M et al. (2017) AAV vector-meditated expression of HLA-G reduces injury-induced corneal vascularization, immune cell infiltration, and fibrosis. Sci Rep 7:17840
Dong, Enheng; Bachleda, Amelia; Xiong, Yubin et al. (2017) Reduced phosphoCREB in Müller glia during retinal degeneration in rd10 mice. Mol Vis 23:90-102
Otis, James M; Namboodiri, Vijay M K; Matan, Ana M et al. (2017) Prefrontal cortex output circuits guide reward seeking through divergent cue encoding. Nature 543:103-107
Bigler, Rebecca L; Kamande, Joyce W; Dumitru, Raluca et al. (2017) Messenger RNAs localized to distal projections of human stem cell derived neurons. Sci Rep 7:611
Guo, Jiami; Otis, James M; Higginbotham, Holden et al. (2017) Primary Cilia Signaling Shapes the Development of Interneuronal Connectivity. Dev Cell 42:286-300.e4
Irvin, David M; McNeill, Robert S; Bash, Ryan E et al. (2017) Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models. Brain Pathol 27:36-50
McCoy, Eric S; Taylor-Blake, Bonnie; Aita, Megumi et al. (2017) Enhanced Nociception in Angelman Syndrome Model Mice. J Neurosci 37:10230-10239

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