C1C. MONOCLONAL ANTIBODY CORE C1C1. Establishment of the Monoclonal Antibody Core: The Monoclonal Antibody Core was established with support from this grant and became operational in June of 2006. The Core currently occupies ~200 sq. ft. space on the 9th floor of the Wood Basic Science Building, and contains laboratory bench space, a clean bench for dissection, a Bio Safety tissue culture hood, two tissue culture incubators, two dissecting microscopes, an ELISA plate reader and a liquid nitrogen freezer (Fig. 8). Dr. Huganir serves as the Director for this facility, and Ms. Min Dai, a full time Research technician with extensive experience |n monoclonal antibody production, is the manager of the facility. Both the space and major equipment for this Core were provided by the Department of Neuroscience (see Appendix, Section 5, for letter of support from Dr. Huganir, Chairman, Department of Neuroscience).

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
5P30NS050274-08
Application #
8441557
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
8
Fiscal Year
2013
Total Cost
$182,695
Indirect Cost
$71,296
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Yang, Hongdian; Kwon, Sung E; Severson, Kyle S et al. (2016) Origins of choice-related activity in mouse somatosensory cortex. Nat Neurosci 19:127-34
Biesecker, Kyle R; Srienc, Anja I; Shimoda, Angela M et al. (2016) Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina. J Neurosci 36:9435-45
Kwon, Sung Eun; Yang, Hongdian; Minamisawa, Genki et al. (2016) Sensory and decision-related activity propagate in a cortical feedback loop during touch perception. Nat Neurosci 19:1243-9
Zhang-Hooks, YingXin; Agarwal, Amit; Mishina, Masayoshi et al. (2016) NMDA Receptors Enhance Spontaneous Activity and Promote Neuronal Survival in the Developing Cochlea. Neuron 89:337-50
Jin, Yunju; Dougherty, Sarah E; Wood, Kevin et al. (2016) Regrowth of Serotonin Axons in the Adult Mouse Brain Following Injury. Neuron 91:748-62
Bharadwaj, Rajnish; Cunningham, Kathleen M; Zhang, Ke et al. (2016) FIG4 regulates lysosome membrane homeostasis independent of phosphatase function. Hum Mol Genet 25:681-92
Roy, Sabyasachi; Zhao, Lingyun; Wang, Xiaoqin (2016) Distinct Neural Activities in Premotor Cortex during Natural Vocal Behaviors in a New World Primate, the Common Marmoset (Callithrix jacchus). J Neurosci 36:12168-12179
Otsu, Yo; Couchman, Kiri; Lyons, Declan G et al. (2015) Calcium dynamics in astrocyte processes during neurovascular coupling. Nat Neurosci 18:210-8
Wang, Han Chin; Lin, Chun-Chieh; Cheung, Rocky et al. (2015) Spontaneous Activity of Cochlear Hair Cells Triggered by Fluid Secretion Mechanism in Adjacent Support Cells. Cell 163:1348-59
Nimmerjahn, Axel; Bergles, Dwight E (2015) Large-scale recording of astrocyte activity. Curr Opin Neurobiol 32:95-106

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