Abstract

C1C. MONOCLONAL ANTIBODY CORE C1C1. Establishment of the Monoclonal Antibody Core: The Monoclonal Antibody Core was established with support from this grant and became operational in June of 2006. The Core currently occupies ~200 sq. ft. space on the 9th floor of the Wood Basic Science Building, and contains laboratory bench space, a clean bench for dissection, a Bio Safety tissue culture hood, two tissue culture incubators, two dissecting microscopes, an ELISA plate reader and a liquid nitrogen freezer (Fig. 8). Dr. Huganir serves as the Director for this facility, and Ms. Min Dai, a full time Research technician with extensive experience |n monoclonal antibody production, is the manager of the facility. Both the space and major equipment for this Core were provided by the Department of Neuroscience (see Appendix, Section 5, for letter of support from Dr. Huganir, Chairman, Department of Neuroscience).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
5P30NS050274-10
Application #
8786462
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
2016-07-14
Budget Start
2014-12-01
Budget End
2015-11-30
Support Year
10
Fiscal Year
2015
Total Cost
$186,999
Indirect Cost
$72,975

  Institution

Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205

  Publications

Kajstura, Tymoteusz J; Dougherty, Sarah E; Linden, David J (2018) Serotonin axons in the neocortex of the adult female mouse regrow after traumatic brain injury. J Neurosci Res 96:512-526
Babola, Travis A; Li, Sally; Gribizis, Alexandra et al. (2018) Homeostatic Control of Spontaneous Activity in the Developing Auditory System. Neuron 99:511-524.e5
Dresselhaus, Erica C; Boersma, Matthew C H; Meffert, Mollie K (2018) Targeting of NF-?B to Dendritic Spines Is Required for Synaptic Signaling and Spine Development. J Neurosci 38:4093-4103
Larson, Valerie A; Mironova, Yevgeniya; Vanderpool, Kimberly G et al. (2018) Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility. Elife 7:
Jiang, Zheng; Yue, Wendy W S; Chen, Lujing et al. (2018) Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells. Cell 175:652-664.e12
Hughes, Ethan G; Orthmann-Murphy, Jennifer L; Langseth, Abraham J et al. (2018) Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex. Nat Neurosci 21:696-706
Minamisawa, Genki; Kwon, Sung Eun; Chevée, Maxime et al. (2018) A Non-canonical Feedback Circuit for Rapid Interactions between Somatosensory Cortices. Cell Rep 23:2718-2731.e6
Zhang, Ke; Daigle, J Gavin; Cunningham, Kathleen M et al. (2018) Stress Granule Assembly Disrupts Nucleocytoplasmic Transport. Cell 173:958-971.e17
Chevée, Maxime; Robertson, Johanna De Jong; Cannon, Gabrielle Heather et al. (2018) Variation in Activity State, Axonal Projection, and Position Define the Transcriptional Identity of Individual Neocortical Projection Neurons. Cell Rep 22:441-455
Chen, Chih-Ming; Orefice, Lauren L; Chiu, Shu-Ling et al. (2017) Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. Proc Natl Acad Sci U S A 114:E619-E628

Showing the most recent 10 out of 83 publications