Administrative Core The Administrative Core of this proposed continuation of the ?JHU Center for Neuroscience Research? NINDS P30 Center is critical for implementation of the primary goal of this Center: to provide the Primary Center Investigators, and other JHU neuroscientists that are engaged in research consistent with the mission of NINDS, with cutting-edge Core services, enhancing their research capabilities to enable fundamental scientific advances in our understanding of the nervous system that have the potential to address critical issues in the treatment of neurological disease. This Core, therefore, includes an administrative structure that allows for fair and equitable use of the two Center Scientific Cores: the Multiphoton Imaging (MPI) Core and the Murine Mutagenesis Core (MMC). It also addresses Scientific Core project prioritization to ensure fair access to the Cores by JHU neuroscience investigators, including: the NINDS-funded Primary Center Investigators, other NINDS-funded JHU investigators, and other neuroscientists at JHU who would benefit from access to the Center. Further, the Administrative Core is proposed to have in place mechanisms that provide a facile means to request Core access, and also strict reporting procedures that provide a record of Core use by all investigators. This includes an assessment of the success of projects performed by the Cores, quantification of services provided by the Cores, and feedback on the quality of Core service. The Administrative Core will oversee all financial issues relating to day-to-day activities of the Cores, and it will provide long-term oversight in order to assure adequate resources are available for all Core services. Finally, the Administrative Core will provide a forum for continual assessment of the quality of Core services and for incorporating into Core services and activities new technologies and, where appropriate, re-organization for Core services to best serve the needs of the users. All of these functions of the Administrative Core will serve to further the NINDS scientific mission by ensuring that this Center for Neuroscience Research functions effectively, efficiently and creatively to assist neuroscientists at JHU SOM in their research efforts.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
5P30NS050274-14
Application #
9700231
Study Section
Special Emphasis Panel (ZNS1)
Project Start
Project End
2021-04-30
Budget Start
2019-05-01
Budget End
2020-04-30
Support Year
14
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Kajstura, Tymoteusz J; Dougherty, Sarah E; Linden, David J (2018) Serotonin axons in the neocortex of the adult female mouse regrow after traumatic brain injury. J Neurosci Res 96:512-526
Babola, Travis A; Li, Sally; Gribizis, Alexandra et al. (2018) Homeostatic Control of Spontaneous Activity in the Developing Auditory System. Neuron 99:511-524.e5
Dresselhaus, Erica C; Boersma, Matthew C H; Meffert, Mollie K (2018) Targeting of NF-?B to Dendritic Spines Is Required for Synaptic Signaling and Spine Development. J Neurosci 38:4093-4103
Larson, Valerie A; Mironova, Yevgeniya; Vanderpool, Kimberly G et al. (2018) Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility. Elife 7:
Jiang, Zheng; Yue, Wendy W S; Chen, Lujing et al. (2018) Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells. Cell 175:652-664.e12
Hughes, Ethan G; Orthmann-Murphy, Jennifer L; Langseth, Abraham J et al. (2018) Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex. Nat Neurosci 21:696-706
Minamisawa, Genki; Kwon, Sung Eun; Chevée, Maxime et al. (2018) A Non-canonical Feedback Circuit for Rapid Interactions between Somatosensory Cortices. Cell Rep 23:2718-2731.e6
Zhang, Ke; Daigle, J Gavin; Cunningham, Kathleen M et al. (2018) Stress Granule Assembly Disrupts Nucleocytoplasmic Transport. Cell 173:958-971.e17
Chevée, Maxime; Robertson, Johanna De Jong; Cannon, Gabrielle Heather et al. (2018) Variation in Activity State, Axonal Projection, and Position Define the Transcriptional Identity of Individual Neocortical Projection Neurons. Cell Rep 22:441-455
Chen, Chih-Ming; Orefice, Lauren L; Chiu, Shu-Ling et al. (2017) Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. Proc Natl Acad Sci U S A 114:E619-E628

Showing the most recent 10 out of 83 publications