In addition to the administrative structures relevant to the individual Cores outlined above, central core administrative functions will also be established to ensure the effective operation of the proposed Center as a integrated whole that will bridge HMS and CHB. A goal of the Administrative Core will be to serve as the glue for the Center to ensure that the cores facilitate the research of Center Investigators and foster collaborative interactions between NINDS-funded scientists in the Longwood Medical Area. In this regard, Dr. Michael E. Greenberg will serve as the overall director and Principal Investigator (PI) for the Center. In addition, the administration of Core usage will be overseen by a Central Steering Committee composed of Dr. Greenberg, Dr. Clifford Woolf (Director of the F.M. Kirby Center for Neurobiology at CHB), Dr. Christopher Walsh (Chief, Division of Genetics at CHB), and the directors of the three individual Cores. Finally, in order to maximize the impact of the Center on neuroscience research, a Core Development Advisory Committee comprised of outside authorities on neuroscience microscopy will advise the PI and Steering Committee on strategic issues concerned with technological development that are relevant to Core services. Taken together, these mechanisms will provide a network of support and communication that will .contribute considerably to the success of the (Center in enhancing existing NINDS research programs and providing new venues for collaboration.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
5P30NS072030-04
Application #
8733767
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Harvard Medical School
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02115
Chow, Brian Wai; Gu, Chenghua (2017) Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation. Neuron 93:1325-1333.e3
Chen, Yao; Granger, Adam J; Tran, Trinh et al. (2017) Endogenous G?q-Coupled Neuromodulator Receptors Activate Protein Kinase A. Neuron 96:1070-1083.e5
Abraira, Victoria E; Kuehn, Emily D; Chirila, Anda M et al. (2017) The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell 168:295-310.e19
Cho, Jin-Hyung; Rendall, Sam D; Gray, Jesse M (2017) Brain-wide maps of Fos expression during fear learning and recall. Learn Mem 24:169-181
Zoeller, Jason J; Bronson, Roderick T; Selfors, Laura M et al. (2017) Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo. NPJ Breast Cancer 3:18
Lutas, Andrew; Lahmann, Carolina; Soumillon, Magali et al. (2016) The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons. Elife 5:
Straub, Christoph; Saulnier, Jessica Lizette; B├Ęgue, Aurelien et al. (2016) Principles of Synaptic Organization of GABAergic Interneurons in the Striatum. Neuron 92:84-92
Jackman, Skyler L; Turecek, Josef; Belinsky, Justine E et al. (2016) The calcium sensor synaptotagmin 7 is required for synaptic facilitation. Nature 529:88-91
Dauth, Stephanie; Grevesse, Thomas; Pantazopoulos, Harry et al. (2016) Extracellular matrix protein expression is brain region dependent. J Comp Neurol 524:1309-36
Park, Sung-Jin; Gazzola, Mattia; Park, Kyung Soo et al. (2016) Phototactic guidance of a tissue-engineered soft-robotic ray. Science 353:158-62

Showing the most recent 10 out of 44 publications