Abstract

IMAGE AND SPECTROSCOPY ANALYSIS AND VISUALIZATION CORE PI: Christophe Lenglet, PhD;co-PI: Noam Harel, PhD This Core will provide advanced analysis tools and resources for a variety of neuroimaging modalities including structural MRI, High Angular Resolution Diffusion Imaging (HARDI), Diffusion Spectroscopic Imaging (DSI), functional MRI (fMRI), intrinsic relaxation parameter imaging, MR spectroscopy (MRS), as well as Positron Emission Tomography (PET) and Computed Tomography (CT). The unique needs of each of these modalities will be served through shared computing equipment, software and expert personnel in the Core. Additionally, the Core will provide support for multi-modality image analysis. Image reconstruction, analysis and visualization require sophisticated mathematical modeling and computational resources. The overall goal of this Core is to provide such unique resources for human and animal neuroimaging research. They will enable individuals to generate high-quality images from high (3 and 4T) and ultrahigh (7T and higher) field MR scanners and to efficiently analyze them through state-of-the-art methods.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
1P30NS076408-01A1
Application #
8538137
Study Section
Special Emphasis Panel (ZNS1-SRB-R (59))
Project Start
Project End
Budget Start
2012-09-30
Budget End
2013-06-30
Support Year
1
Fiscal Year
2012
Total Cost
$114,617
Indirect Cost
$39,211

  Institution

Name
University of Minnesota Twin Cities
Department
Type
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Park, Young Woo; Deelchand, Dinesh K; Joers, James M et al. (2018) AutoVOI: real-time automatic prescription of volume-of-interest for single voxel spectroscopy. Magn Reson Med 80:1787-1798
Marja?ska, Ma?gorzata; Deelchand, Dinesh K; Hodges, James S et al. (2018) Altered macromolecular pattern and content in the aging human brain. NMR Biomed 31:
U?urbil, Kamil (2018) Imaging at ultrahigh magnetic fields: History, challenges, and solutions. Neuroimage 168:7-32
Peña, Edgar; Zhang, Simeng; Patriat, Remi et al. (2018) Multi-objective particle swarm optimization for postoperative deep brain stimulation targeting of subthalamic nucleus pathways. J Neural Eng 15:066020
Wu, Xiaoping; Auerbach, Edward J; Vu, An T et al. (2018) High-resolution whole-brain diffusion MRI at 7T using radiofrequency parallel transmission. Magn Reson Med 80:1857-1870
Moerel, Michelle; De Martino, Federico; U?urbil, Kâmil et al. (2018) Evaluating the Columnar Stability of Acoustic Processing in the Human Auditory Cortex. J Neurosci 38:7822-7832
Adanyeguh, Isaac M; Perlbarg, Vincent; Henry, Pierre-Gilles et al. (2018) Autosomal dominant cerebellar ataxias: Imaging biomarkers with high effect sizes. Neuroimage Clin 19:858-867
Zhu, Xiao-Hong; Lu, Ming; Chen, Wei (2018) Quantitative imaging of brain energy metabolisms and neuroenergetics using in vivo X-nuclear 2H, 17O and 31P MRS at ultra-high field. J Magn Reson 292:155-170
Zhang, Simeng; Connolly, Allison T; Madden, Lauren R et al. (2018) High-resolution local field potentials measured with deep brain stimulation arrays. J Neural Eng 15:046019
Deelchand, Dinesh K; Auerbach, Edward J; Marja?ska, Ma?gorzata (2018) Apparent diffusion coefficients of the five major metabolites measured in the human brain in vivo at 3T. Magn Reson Med 79:2896-2901

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