IMAGE AND SPECTROSCOPY ANALYSIS AND VISUALIZATION CORE PI: Christophe Lenglet, PhD;co-PI: Noam Harel, PhD This Core will provide advanced analysis tools and resources for a variety of neuroimaging modalities including structural MRI, High Angular Resolution Diffusion Imaging (HARDI), Diffusion Spectroscopic Imaging (DSI), functional MRI (fMRI), intrinsic relaxation parameter imaging, MR spectroscopy (MRS), as well as Positron Emission Tomography (PET) and Computed Tomography (CT). The unique needs of each of these modalities will be served through shared computing equipment, software and expert personnel in the Core. Additionally, the Core will provide support for multi-modality image analysis. Image reconstruction, analysis and visualization require sophisticated mathematical modeling and computational resources. The overall goal of this Core is to provide such unique resources for human and animal neuroimaging research. They will enable individuals to generate high-quality images from high (3 and 4T) and ultrahigh (7T and higher) field MR scanners and to efficiently analyze them through state-of-the-art methods.

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZNS1-SRB-R (59))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Minnesota Twin Cities
United States
Zip Code
Wilson, Sylia; Malone, Stephen M; Hunt, Ruskin H et al. (2017) Problematic alcohol use and hippocampal volume in a female sample: disentangling cause from consequence using a co-twin control study design. Psychol Med :1-12
Marja?ska, Ma?gorzata; McCarten, J Riley; Hodges, James et al. (2017) Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using 1H magnetic resonance spectroscopy at 7 T. Neuroscience 354:168-177
Cheong, Ian; Marja?ska, Ma?gorzata; Deelchand, Dinesh K et al. (2017) Ultra-High Field Proton MR Spectroscopy in Early-Stage Amyotrophic Lateral Sclerosis. Neurochem Res 42:1833-1844
Ramsay, Ian S; Nienow, Tasha M; MacDonald 3rd, Angus W (2017) Increases in Intrinsic Thalamocortical Connectivity and Overall Cognition Following Cognitive Remediation in Chronic Schizophrenia. Biol Psychiatry Cogn Neurosci Neuroimaging 2:355-362
Liu, Jiaen; Shao, Qi; Wang, Yicun et al. (2017) In vivo imaging of electrical properties of an animal tumor model with an 8-channel transceiver array at 7?T using electrical properties tomography. Magn Reson Med 78:2157-2169
Santoro, Roberta; Moerel, Michelle; De Martino, Federico et al. (2017) Reconstructing the spectrotemporal modulations of real-life sounds from fMRI response patterns. Proc Natl Acad Sci U S A 114:4799-4804
Zeydan, Burcu; Deelchand, Dinesh K; Tosakulwong, Nirubol et al. (2017) Decreased Glutamate Levels in Patients with Amnestic Mild Cognitive Impairment: An sLASER Proton MR Spectroscopy and PiB-PET Study. J Neuroimaging 27:630-636
Joers, James M; Deelchand, Dinesh K; Kumar, Anjali et al. (2017) Measurement of Hypothalamic Glucose Under Euglycemia and Hyperglycemia by MRI at 3T. J Magn Reson Imaging 45:681-691
Deelchand, Dinesh K; Auerbach, Edward J; Marja?ska, Ma?gorzata (2017) Apparent diffusion coefficients of the five major metabolites measured in the human brain in vivo at 3T. Magn Reson Med :
Wang, Xiao; Zhu, Xiao-Hong; Zhang, Yi et al. (2017) A comparison study between the saturation-recovery-T1 and CASL MRI methods for quantitative CBF imaging. Magn Reson Imaging 37:179-186

Showing the most recent 10 out of 144 publications