The administrative structure places the responsibilify for this NINDS P30 Core Grant largely in the hands of the Program Director and Steering Committee;the steering committee is composed of the Program Director (Dr. Lipton at SBMRI) plus Pis of two of the qualifying projects (Huaxi Xu of SBMRI and Al La Spada of UCSD) and the directors of each Core (Dongxian Zhang/Electrophysiology-Optogenetics, Marc Mercola/HT Library Screening, Eliezer Masliah/Neuropathology). This group represents a wide range of neuroscience interests and senior leadership. Additionally, Dr. Stephen F. Heinemann, head of the Neurobiology Laboratory at the Salk Institute and Adjunct Professor at UCSD and SBMRI (and a member of the SBMRI Scientific Advisory Board), will serve as an Advisor to the group. Dr. Heinemann has served as president of the Sociefy for Neuroscience (SfN), and Dr. Lipton as head of the Education Committee of the SfN (which ran all of the courses at the annual meeting), and therefore both have nationally-recognized organizational and leadership skills. Additionally, the head of Finance at SBMRI, Antony Peake, will oversee the use of funds. Decisions regarding Core Usage are outiined under each Core and will be administered by each Core Director in consultation with this Steering Committee;the Core Directors, as part of the Core Steering Committee, will meet every month. At these meetings, coordination of ongoing neuroscience research among the Cores and area institutions will be discussed, as well as access of other neuroscience projects to the Cores as needed.

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Center Core Grants (P30)
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Application #
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
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Sanford-Burnham Medical Research Institute
La Jolla
United States
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Fields, Jerel Adam; Serger, Elisabeth; Campos, Sofia et al. (2016) HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders. Neurobiol Dis 86:154-69
Nakanishi, Nobuki; Kang, Yeon-Joo; Tu, Shichun et al. (2016) Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model. J Mol Neurosci 58:59-65
Valera, Elvira; Masliah, Eliezer (2016) Combination therapies: The next logical Step for the treatment of synucleinopathies? Mov Disord 31:225-34
Sanz-Blasco, Sara; Piña-Crespo, Juan C; Zhang, Xiaofei et al. (2016) Levetiracetam inhibits oligomeric Aβ-induced glutamate release from human astrocytes. Neuroreport 27:705-9
Nakamura, Tomohiro; Lipton, Stuart A (2016) Nitrosative Stress in the Nervous System: Guidelines for Designing Experimental Strategies to Study Protein S-Nitrosylation. Neurochem Res 41:510-4
Sunico, Carmen R; Sultan, Abdullah; Nakamura, Tomohiro et al. (2016) Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons. Proc Natl Acad Sci U S A 113:E7564-E7571
Valera, E; Monzio Compagnoni, G; Masliah, E (2016) Review: Novel treatment strategies targeting alpha-synuclein in multiple system atrophy as a model of synucleinopathy. Neuropathol Appl Neurobiol 42:95-106
Gillman, Alan L; Lee, Joon; Ramachandran, Srinivasan et al. (2016) Small molecule NPT-440-1 inhibits ionic flux through Aβ1-42 pores: Implications for Alzheimer's disease therapeutics. Nanomedicine 12:2331-2340
Akhtar, Mohd Waseem; Sanz-Blasco, Sara; Dolatabadi, Nima et al. (2016) Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation. Nat Commun 7:10242
Nakamura, Tomohiro; Prikhodko, Olga A; Pirie, Elaine et al. (2015) Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases. Neurobiol Dis 84:99-108

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