The Administration of the Yeast Resource Center will build on strategies learned and used by the center over the last 20 years of funding in the successful management of a Biomedical Technology Research Resource. The greatest strength of our center is a highly experienced and diverse team of investigators that have worked together for a very long time. Our close and effective working relationship is evident by our long and productive resource. Our center is unique amongst the NIGMS Biotechnology Research Resources in that, unlike many other centers that focus on a single technology, our resource leverages an experimental system using many technologies to drive biomedical research. We will continue to use the administrative capabilities we have put in place over the last two decades to ensure an effective and functioning resource for the scientific community.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Biotechnology Resource Grants (P41)
Project #
2P41GM103533-21
Application #
9208070
Study Section
Special Emphasis Panel (ZRG1)
Project Start
1997-09-30
Project End
2022-03-31
Budget Start
2017-01-01
Budget End
2017-12-31
Support Year
21
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Conkar, Deniz; Culfa, Efraim; Odabasi, Ezgi et al. (2017) The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking. J Cell Sci 130:1450-1462
Widjaja, Christella E; Olvera, Jocelyn G; Metz, Patrick J et al. (2017) Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification. J Clin Invest 127:3609-3623
Hope, Elyse A; Amorosi, Clara J; Miller, Aaron W et al. (2017) Experimental Evolution Reveals Favored Adaptive Routes to Cell Aggregation in Yeast. Genetics 206:1153-1167
Callens, Céline; Coelho, Nelson C; Miller, Aaron W et al. (2017) A multiplex culture system for the long-term growth of fission yeast cells. Yeast 34:343-355
May, Damon H; Tamura, Kaipo; Noble, William S (2017) Param-Medic: A Tool for Improving MS/MS Database Search Yield by Optimizing Parameter Settings. J Proteome Res 16:1817-1824
Hanna 4th, Michael G; Block, Samuel; Frankel, E B et al. (2017) TFG facilitates outer coat disassembly on COPII transport carriers to promote tethering and fusion with ER-Golgi intermediate compartments. Proc Natl Acad Sci U S A 114:E7707-E7716
Subramanian, Kanagaraj; Rauniyar, Navin; Lavalleé-Adam, Mathieu et al. (2017) Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease. Mol Cell Proteomics 16:1938-1957
Zimmerman, Sandra G; Merrihew, Gennifer E; MacCoss, Michael J et al. (2017) Proteomics Analysis Identifies Orthologs of Human Chitinase-Like Proteins as Inducers of Tube Morphogenesis Defects in Drosophila melanogaster. Genetics 206:973-984
Ma, Yuanhui; McClatchy, Daniel B; Barkallah, Salim et al. (2017) HILAQ: A Novel Strategy for Newly Synthesized Protein Quantification. J Proteome Res 16:2213-2220
Cao, Liwei; Diedrich, Jolene K; Kulp, Daniel W et al. (2017) Global site-specific N-glycosylation analysis of HIV envelope glycoprotein. Nat Commun 8:14954

Showing the most recent 10 out of 328 publications