Mechanistic issues in BOLD based fMRI were further examined by comparing BOLD images with perfusion change measurements, demonstrating that in gray matter areas in the visual cortex, absolute and relative CBF changes in humans during photic stimulation were 31 1 11 SD ml/100 g tissue/min and 43 1 16 SD% (n = 12), respectively, while the relative oxygen consumption change was close to zero. These findings were in agreement with previous results using positron emission tomography.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR008079-10
Application #
6609291
Study Section
Project Start
2002-06-01
Project End
2003-05-31
Budget Start
Budget End
Support Year
10
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
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