This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.PurposeTo examine relationships between specific energy absorption rate (SAR) and temperature distributions in the human head during radio frequency energy deposition in MRI.Materials and MethodsA multi-tissue numerical model of the head was developed that considered thermal conductivity, heat capacity, perfusion, heat of metabolism, electrical properties, and density. Calculations of SAR and the resulting temperature increase were performed for different coils at different frequencies.ResultsBecause of tissue-dependant perfusion rates and thermal conduction, there is not a good overall spatial correlation between SAR and temperature increase. When a volume coil is driven to induce a head average SAR level of either 3.0 or 3.2 W/kg, it is unlikely that a significant temperature increase in the brain will occur due to its high rate of perfusion, although limits on SAR in any 1 g of tissue in the head may be exceeded.ConclusionAttempts to ensure RF safety in MRI often rely on assumptions about local temperature from local SAR levels. The relationship between local SAR and local temperature is not, however, straightforward. In cases where high SAR levels are required due to pulse sequence demands, calculations of temperature may be preferable to calculations of SAR because of the more direct relationship between temperature and safety.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
2P41RR008079-16
Application #
7721357
Study Section
Special Emphasis Panel (ZRG1-SBIB-S (40))
Project Start
2008-06-01
Project End
2009-05-31
Budget Start
2008-06-01
Budget End
2009-05-31
Support Year
16
Fiscal Year
2008
Total Cost
$71,340
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
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