This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Purpose: Cardiac motion causes significant artifact in breast MRI. Conventional slab saturation pulses cannot be applied to the heart without obscuring portions of the axillary breast tissue. We have implemented a 2D cylindrical saturation pulse that selectively saturates the heart and diaphragm. Methods: We collected data on six healthy volunteers at 1.5T (GE Healthcare, Waukesha, WI). A 2D excitation was applied with spiral gradients in both x and z for an elliptical cylindrical superior-inferior prescription encompassing the heart. Gradient crushers followed the cylindrical excitation, thus dephasing and reducing the signal from the selected area. The heart saturation pulse was followed by a dual band spectral spatial RF pulse for bilateral breast excitation, and a 3D variable-density stack of spirals for acquisition. The TR for the saturation pulse is 12 ms, in addition to the 32 ms bilateral spiral pulse. For analysis, three ROIs were drawn in each image: one in the heart, one in the glandular breast tissue, and one in the image background. To calculate the signal emanating from the outer area, the standard deviation of the outer ROI was normalized by dividing by the mean signal from the breast ROI. To read about other projects ongoing at the Lucas Center, please visit http://rsl.stanford.edu/ (Lucas Annual Report and ISMRM 2011 Abstracts)

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR009784-17
Application #
8362952
Study Section
Special Emphasis Panel (ZRG1-SBIB-U (40))
Project Start
2011-04-01
Project End
2012-03-31
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
17
Fiscal Year
2011
Total Cost
$19,531
Indirect Cost
Name
Stanford University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Taviani, Valentina; Alley, Marcus T; Banerjee, Suchandrima et al. (2017) High-resolution diffusion-weighted imaging of the breast with multiband 2D radiofrequency pulses and a generalized parallel imaging reconstruction. Magn Reson Med 77:209-220
Guo, Jia; Holdsworth, Samantha J; Fan, Audrey P et al. (2017) Comparing accuracy and reproducibility of sequential and Hadamard-encoded multidelay pseudocontinuous arterial spin labeling for measuring cerebral blood flow and arterial transit time in healthy subjects: A simulation and in vivo study. J Magn Reson Imaging :
Uecker, Martin; Lustig, Michael (2017) Estimating absolute-phase maps using ESPIRiT and virtual conjugate coils. Magn Reson Med 77:1201-1207
Lai, Lillian M; Cheng, Joseph Y; Alley, Marcus T et al. (2017) Feasibility of ferumoxytol-enhanced neonatal and young infant cardiac MRI without general anesthesia. J Magn Reson Imaging 45:1407-1418
Kogan, Feliks; Hargreaves, Brian A; Gold, Garry E (2017) Volumetric multislice gagCEST imaging of articular cartilage: Optimization and comparison with T1rho. Magn Reson Med 77:1134-1141
Aksoy, Murat; Maclaren, Julian; Bammer, Roland (2017) Prospective motion correction for 3D pseudo-continuous arterial spin labeling using an external optical tracking system. Magn Reson Imaging 39:44-52
Tamir, Jonathan I; Uecker, Martin; Chen, Weitian et al. (2017) T2 shuffling: Sharp, multicontrast, volumetric fast spin-echo imaging. Magn Reson Med 77:180-195
Vos, Sjoerd B; Aksoy, Murat; Han, Zhaoying et al. (2016) Trade-off between angular and spatial resolutions in in vivo fiber tractography. Neuroimage 129:117-132
Suh, Ga-Young; Choi, Gilwoo; Herfkens, Robert J et al. (2016) Three-Dimensional Modeling Analysis of Visceral Arteries and Kidneys during Respiration. Ann Vasc Surg 34:250-60
Ong, Frank; Lustig, Michael (2016) Beyond Low Rank + Sparse: Multi-scale Low Rank Matrix Decomposition. IEEE J Sel Top Signal Process 10:672-687

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