This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objective of this work is to explore techniques for improvements in imaging cancer with genetically encoded magnetite using magnetic resonance imaging. Magnetotactic bacteria AMB-1 produce magnetite particles and colonize tumors in mice following systemic delivery [1]. Several techniques exist for visualization of the magnetite particles, but accurate quantitation in vivo remains challenging. In this work, two methods were implemented for positive contrast imaging and quantitative detection of the magnetite particles on the 7T animal scanner.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR009784-17
Application #
8362967
Study Section
Special Emphasis Panel (ZRG1-SBIB-U (40))
Project Start
2011-04-01
Project End
2012-03-31
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
17
Fiscal Year
2011
Total Cost
$19,531
Indirect Cost
Name
Stanford University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Taviani, Valentina; Alley, Marcus T; Banerjee, Suchandrima et al. (2017) High-resolution diffusion-weighted imaging of the breast with multiband 2D radiofrequency pulses and a generalized parallel imaging reconstruction. Magn Reson Med 77:209-220
Guo, Jia; Holdsworth, Samantha J; Fan, Audrey P et al. (2017) Comparing accuracy and reproducibility of sequential and Hadamard-encoded multidelay pseudocontinuous arterial spin labeling for measuring cerebral blood flow and arterial transit time in healthy subjects: A simulation and in vivo study. J Magn Reson Imaging :
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Ong, Frank; Lustig, Michael (2016) Beyond Low Rank + Sparse: Multi-scale Low Rank Matrix Decomposition. IEEE J Sel Top Signal Process 10:672-687

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