The Research Translation Core (RTC) of the UW Superfund Basic Research Program is well positioned to assist SBRP investigators in disseminating important research findings and new technology to a wide spectrum of stakeholders.
The Specific Aims of the Core address the required components described in the SBRP request for applications: Government Agency Partnerships, Technology Transfer, and Communicating to Broad Audiences. The core will continue to: 1) develop communication strategies to exchange information regarding government agency priorities and emerging SBRP research findings. An Agency Seminar Series has been set-up to support experts who can help agency staff address local hazardous waste and contamination issues, 2) assist investigators in moving UW SBRP research findings into application through partnerships with the UW Tech Transfer office. The Core co-director and staff meet with SBRP investigators regularly to identify potential patents and leverage open-source approaches to advance research findings, 3) provide critical information to individual stakeholders by identifying key communication venues and materials with government agencies and community groups. Procedures and materials will be developed for communities concerned about impacts from environmental contaminants, local and state agencies concerned about their community outreach, and for disease advocacy groups and health professionals interested in environmental health education. Annual workshops and print/web materials will used to increase dissemination of current research findings between SBRP investigators, agency staff and community members, 4) partner with Community Groups. The UW SBRP has a long history of working with Tribal Nations, community groups, health professionals, and individual stakeholders to address environmental health concerns. The scope of activities will broaden to include new collaborations, and 5) work with the Administrative Core to refine a Research Translation and Outreach Tracking System to provide documentation and reporting of Core activities on an ongoing basis. The UW SBRP focuses most intensively on developing early biomarkers of adverse effects to human health and the environment from neurotoxic chemicals. Developing early indicators of health effects from exposures to neurotoxic compounds is a theme that resonates with the scientific community, governmental agencies who are involved with hazardous waste sites and the public as a whole.

Public Health Relevance

Research Translation Cores of the NIEHS SBPR perform an integral role in the overarching SBRP goal of protecting human health. The UW Research Translation Core assists project investigators in disseminating important research findings and new technologies to a wide spectrum of stakeholders. The core informs constituents of relevant research related to health effects of neurotoxic compounds and promotes interactions between communities living near hazardous waste sites and the associated governmental agencies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES004696-25
Application #
8377598
Study Section
Special Emphasis Panel (ZES1-LKB-D)
Project Start
Project End
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
25
Fiscal Year
2012
Total Cost
$208,379
Indirect Cost
$70,520
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Furlong, Clement E; Marsillach, Judit; Jarvik, Gail P et al. (2016) Paraoxonases-1, -2 and -3: What are their functions? Chem Biol Interact :
Cole, Toby B; Coburn, Jacki; Dao, Khoi et al. (2016) Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain. Toxicology 374:1-9
Roqué, Pamela J; Dao, Khoi; Costa, Lucio G (2016) Microglia mediate diesel exhaust particle-induced cerebellar neuronal toxicity through neuroinflammatory mechanisms. Neurotoxicology 56:204-214
Garrick, Jacqueline M; Dao, Khoi; de Laat, Rian et al. (2016) Developmental expression of paraoxonase 2. Chem Biol Interact 259:168-174
Ramsden, Richard; Gallagher, Evan P (2016) Dual NRF2 paralogs in Coho salmon and their antioxidant response element targets. Redox Biol 9:114-123
Meador, James P; Yeh, Andrew; Young, Graham et al. (2016) Contaminants of emerging concern in a large temperate estuary. Environ Pollut 213:254-67
Wang, Lu; Espinoza, Herbert M; MacDonald, James W et al. (2016) Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury. Toxicol Sci 149:145-57
Marsillach, Judit; Costa, Lucio G; Furlong, Clement E (2016) Paraoxonase-1 and Early-Life Environmental Exposures. Ann Glob Health 82:100-10
Costa, Lucio G; Garrick, Jacqueline M; Roquè, Pamela J et al. (2016) Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More. Oxid Med Cell Longev 2016:2986796
Kim, Daniel Seung; Burt, Amber A; Ranchalis, Jane E et al. (2015) PLTP activity inversely correlates with CAAD: effects of PON1 enzyme activity and genetic variants on PLTP activity. J Lipid Res 56:1351-62

Showing the most recent 10 out of 427 publications