The Administrative Core has primary responsibility for oversight and guidance of the University of North Carolina at Chapel Hill Superfund Research Program (UNC-CH SRP). This includes the overall planning and coordination of UNC-SRP research activities, fostering interdisciplinary interaction, enriching the program through seminars and retreats, scheduling meetings of Program researchers and trainees, the Executive Committee and the External Advisory Committee, as well as fiscal and resource management and planning. The proposed UNC-SRP includes five research projects, two research support cores, a Research Translation Core, and the Administrative Core. The Administrative Core will continue to be led by Professor Swenberg, Director of the UNC SRP. He will be assisted by Professor Rusyn, Core Co-Leader, and Ms. Nataliya Vanchosovych, Program Coordinator. The goals of the core are to: (1) foster strong interdisciplinary interactions and high productivity of the research projects and cores;(2) manage the fiscal resources of the program;(3) organize and schedule monthly meetings of all UNC-SRP researchers, including students and post-docs during the academic year, monthly meetings of the Executive Committee (immediately before or after monthly Program meetings), enrichment seminars, and annual meetings of the External Advisory Committee (in conjunction with an annual retreat);and (4) facilitate interactions of our scientists and trainees with the Research Translation Core to maximize communication with the National Institute of Environmental Health Sciences, the U.S. Environmental Protection Agency, the Agency for Toxic Substances and Disease Registry, the North Carolina Department of Environment and Natural Resources, other government agencies, communities, the public, and potential users of the technology developed by our SRP, in translating research concepts developed in our Program.

Public Health Relevance

Since its inception, the UNC-CH SRP has prioritized its research to address the scientific underpinnings of risk assessment and the development of improved methods for remediation, with goals of more accurately assessing exposure and risks and more efficiently reducing risks by remediation of hazardous waste sites. The Administrative Core will continue to further advance these public health goals.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
3P42ES005948-21S1
Application #
8885021
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
21
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
City
Chapel Hill
State
NC
Country
United States
Zip Code
Reif, David M; Truong, Lisa; Mandrell, David et al. (2016) High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes. Arch Toxicol 90:1459-70
Brooks, Samira A; Martin, Elizabeth; Smeester, Lisa et al. (2016) miRNAs as common regulators of the transforming growth factor (TGF)-β pathway in the preeclamptic placenta and cadmium-treated trophoblasts: Links between the environment, the epigenome and preeclampsia. Food Chem Toxicol 98:50-57
Wu, Tao P; Wang, Tao; Seetin, Matthew G et al. (2016) DNA methylation on N(6)-adenine in mammalian embryonic stem cells. Nature 532:329-33
Zabinski, Joseph W; Garcia-Vargas, Gonzalo; Rubio-Andrade, Marisela et al. (2016) Advancing Dose-Response Assessment Methods for Environmental Regulatory Impact Analysis: A Bayesian Belief Network Approach Applied to Inorganic Arsenic. Environ Sci Technol Lett 3:200-204
Tian, Xu; Patel, Keyur; Ridpath, John R et al. (2016) Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium. PLoS One 11:e0167503
Smith, Martyn T; Guyton, Kathryn Z; Gibbons, Catherine F et al. (2016) Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis. Environ Health Perspect 124:713-21
Chappell, Grace; Silva, Grace O; Uehara, Takeki et al. (2016) Characterization of copy number alterations in a mouse model of fibrosis-associated hepatocellular carcinoma reveals concordance with human disease. Cancer Med 5:574-85
Sharma, Vyom; Collins, Leonard B; Chen, Ting-Huei et al. (2016) Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations. Oncotarget 7:25377-90
Lai, Yongquan; Yu, Rui; Hartwell, Hadley J et al. (2016) Measurement of Endogenous versus Exogenous Formaldehyde-Induced DNA-Protein Crosslinks in Animal Tissues by Stable Isotope Labeling and Ultrasensitive Mass Spectrometry. Cancer Res 76:2652-61
Adrion, Alden C; Nakamura, Jun; Shea, Damian et al. (2016) Screening Nonionic Surfactants for Enhanced Biodegradation of Polycyclic Aromatic Hydrocarbons Remaining in Soil After Conventional Biological Treatment. Environ Sci Technol 50:3838-45

Showing the most recent 10 out of 453 publications