The Training Core of the UC San Diego Superfund Program supports the interdisciplinary education of junior scientists to become the next generation of environmental researchers in the Environmental Health Sciences. It is a multidisciplinary program at the crossroads of biology, chemistry and environmental sciences which converge in our Superfund program. Our faculty members are affiliated with one or more of several graduate training programs: Chemistry &Biochemistry, Biological Sciences, Biomedical Sciences, and Neurosciences at UCSD or The Scripps Research Institute graduate program, each of which is independently organized and most are multidisciplinary and multi-departmental. Thus, while the supported graduate students may be based in dramatically different scientific disciplines, they share focused interest in environmental health sciences and participate in educational opportunities through meetings, seminar programs, the Community Engagement Core, the Research Translation Core, teaching opportunities, and required classes focused in molecular toxicology and toxicogenomics, ethics, statistics, and environmental health. Training students from a variety of graduate programs in interdisciplinary approaches to environmental sciences is novel and unique. Our program fosters predoctoral training that specifically addresses issues related to environmental health and such programs are critical for the preparation of young investigators to undertake the research so important to improving our environment and providing key information related to toxics in human health. Thus, the interdisciplinary training of Ph.D. graduate students within the extremely rich environment of the UCSD Superfund Program Center, will continue to create a cadre of dedicated, cutting-edge Environmental Health research leaders for the future.

Public Health Relevance

The next generation of environmental health scientists will need to integrate a broader array of skill sets than any other in history. As our environmental challenges become greater, the cadre of scientific professionals required to analyze and solve them will need to be trained in state-of-the-art technologies in a wide variety of fields such as those represented by our Superfund laboratories at UCSD.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES010337-13
Application #
8659432
Study Section
Special Emphasis Panel ()
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
13
Fiscal Year
2014
Total Cost
$154,053
Indirect Cost
$38,492
Name
University of California San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Hoffmann, Hanne M; Gong, Ping; Tamrazian, Anika et al. (2018) Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner. Mol Cell Endocrinol 461:143-154
Zhong, Zhenyu; Liang, Shuang; Sanchez-Lopez, Elsa et al. (2018) New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. Nature 560:198-203
Wei, Zong; Yoshihara, Eiji; He, Nanhai et al. (2018) Vitamin D Switches BAF Complexes to Protect ? Cells. Cell 173:1135-1149.e15
Caussy, Cyrielle; Hsu, Cynthia; Lo, Min-Tzu et al. (2018) Link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD. Hepatology :
McNulty, Reginald; Cardone, Giovanni; Gilcrease, Eddie B et al. (2018) Cryo-EM Elucidation of the Structure of Bacteriophage P22 Virions after Genome Release. Biophys J 114:1295-1301
Song, Na-Young; Zhu, Feng; Wang, Zining et al. (2018) IKK? inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways. Proc Natl Acad Sci U S A 115:E812-E821
Song, Isabelle Jingyi; Yang, Yoon Mee; Inokuchi-Shimizu, Sayaka et al. (2018) The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice. Int J Cancer 142:81-91
Hoffmann, Hanne; Pandolfi, Erica; Larder, Rachel et al. (2018) Haploinsufficiency of Homeodomain Proteins Six3, Vax1, and Otx2, Causes Subfertility in Mice Via Distinct Mechanisms. Neuroendocrinology :
Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y et al. (2018) Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A 115:E9879-E9888
Kim, Ju Youn; Garcia-Carbonell, Ricard; Yamachika, Shinichiro et al. (2018) ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. Cell 175:133-145.e15

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