Center Director, Dr. Robert Tukey, will head of the Administrative Core and will ensure that the individual research projects and cores meet the goals outlined by NIEHS and operate in a highly integrated fashion. The overall objective of this core is to foster effective science-to-science-communication internally within the SRP UC San Diego Center (UCSS SRC), and to disseminate these findings in a way that will be useful to government agencies and our collaborative partners. Through technology transfer and data dissemination, this process will ensure that the sharing of our research efforts will have the greatest impact on society. With assistance from Dr. Michael Karin, the Deputy/Scientific Director, and Michelle Feiock, the Center Administrator, the Director will lead the core in achieving its three main aims: 1) To plan and coordinate research activities: The staff of the Administrative Core will work together to provide the necessary services to meet the needs of the research faculty and to assure that their projects operate in a smooth and efficient fashion. The Administrative Core will also work with the individual Project and Core Leaders, Research Translation Core and the UCSD Technology Transfer office to examine the commercial applicability of and facilitate the translation of applicable technologies developed during the funding period. 2) To integrate cross-disciplinary research through communication: The core will serve as a central point of contact for the organization of all program meetings including Internal and External Advisory Committees, on-campus and off campus Community Engagement Core (CEC) and Research Translation Core (RTC) meetings, Distinguished Seminar Series, monthly Principal Investigator seminar series, and other working group meetings such as graduate student seminars. In collaboration with Michelle Feiock, the Director will coordinate all of the administrative activities of the UCSD SRC, and ensure that effective and timely communications are occurring with government agencies and research partners. The Administrative Core is also responsible for coordinating yearly travel of the trainees and investigators to the yearly NIEHS Superfund Annual Meeting. 3) Oversee the financial and resource management of the program: Michelle Feiock, Center Administrator, will direct all financial aspects of the program. Through consistent communication, she will ensure each Project/Core is up to date regarding their financial status, thus enabling them to effectively achieve their research aims. In coordination with University staff, she will also provide NIEHS with all required documents, including the P42 Center Annual Updates and the non-competitive competitive renewals.

Public Health Relevance

While an organizational structure is critical to maintaining the daily operation of the UC San Diego SRC, the Administrative Core is the point of contact for disseminating relevant information pertinent to public health by leveraging the activities of the Research Translation Core. Thus, new research findings and technologies are shared with government partners, EPA, and local agencies, as well as other SRCs and the NIEHS.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES010337-18
Application #
9687700
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2019-04-01
Budget End
2020-03-31
Support Year
18
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of California, San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y et al. (2018) Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A 115:E9879-E9888
Kim, Ju Youn; Garcia-Carbonell, Ricard; Yamachika, Shinichiro et al. (2018) ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. Cell 175:133-145.e15
Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin et al. (2018) Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301-306
Fan, Weiwei; He, Nanhai; Lin, Chun Shi et al. (2018) ERR? Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1?/?-Deficient Muscle. Cell Rep 22:2521-2529
Brouha, Sharon S; Nguyen, Phirum; Bettencourt, Ricki et al. (2018) Increased severity of liver fat content and liver fibrosis in non-alcoholic fatty liver disease correlate with epicardial fat volume in type 2 diabetes: A prospective study. Eur Radiol 28:1345-1355
Hsu, Po-Kai; Takahashi, Yohei; Munemasa, Shintaro et al. (2018) Abscisic acid-independent stomatal CO2 signal transduction pathway and convergence of CO2 and ABA signaling downstream of OST1 kinase. Proc Natl Acad Sci U S A 115:E9971-E9980
Dhar, Debanjan; Antonucci, Laura; Nakagawa, Hayato et al. (2018) Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling. Cancer Cell 33:1061-1077.e6
Febbraio, Mark A; Reibe, Saskia; Shalapour, Shabnam et al. (2018) Preclinical Models for Studying NASH-Driven HCC: How Useful Are They? Cell Metab :
Fujiwara, Ryoichi; Yoda, Emiko; Tukey, Robert H (2018) Species differences in drug glucuronidation: Humanized UDP-glucuronosyltransferase 1 mice and their application for predicting drug glucuronidation and drug-induced toxicity in humans. Drug Metab Pharmacokinet 33:9-16
Hartmann, Phillipp; Hochrath, Katrin; Horvath, Angela et al. (2018) Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice. Hepatology 67:2150-2166

Showing the most recent 10 out of 404 publications