The RTC will enable the CU Center to address issues of high relevance, maximize program investments, and foster innovation while promoting cutting-edge research on the health impacts and geochemistry of Arsenic (As) and Manganese (Mn) via drinking water primarily from groundwater. Our emphasis is on government partnerships, including EPA, ATSDR and local/state agencies managing groundwater drinking water supplies. RTC will work with each Project PI and the Community Engagement Core (CEC) to engage in constructive collaborations with agencies that can benefit from our expertise. The RTC will facilitate interactions with site managers of the Vineland Superfund (SF) site (i.e., EPA, USACE, NJDEP) where CU scientists will work on applying accelerated remediation approaches. With NJDEP, NJGS, USGS and local county DOH partners, we will produce a proof of concept for 3-D risk based maps of As for sitting private wells and create educational videos for residents with arsenic in their wells. The RTC and GIS partners at EPA, ATSDR, and IH will develop and utilize state-of-the art geospatial and analytical tools. Updates to CU SRP online mapping service will identify and analyze the impacts of SF sites on vulnerable populations, to more effectively remediate high priority sites. We will communicate novel findings from our biomedical research to broad audiences via organized forums in the US and Bangladesh. Research translation will be augmented by monthly multidisciplinary seminars, information exchange forums, and targeted meetings. Our EPA partners will announce selected CU SRP seminars via TechDirect (with 37,000+ subscribers) and broadcast them via the online CLU-IN service. We will increase our collaborations with other Centers and SF agencies in planning the SRP Annual Meeting, RTC workshops, Partnership for Environmental Public Health, and other EPA, NIEHS, and ATSDR events. We will inform NIEHS of our Center's research briefs, publications, and success stories on a regular basis via phone, emails, and the online SRP data form. Our own website will be updated on an ongoing basis, profiling CU research &scientists and linking to key resources from EPA, NIEHS, SRP websites and to local issues of interest to the general public.

Public Health Relevance

Research translation can augment and accelerate the impact of basic and applied science on public policies, regulations, and human behavior thereby providing greater protection to the public from adverse exposures to As and Mn in drinking water.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES010349-12
Application #
8461589
Study Section
Special Emphasis Panel (ZES1-JAB-J)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
12
Fiscal Year
2013
Total Cost
$143,822
Indirect Cost
$57,597
Name
Columbia University (N.Y.)
Department
Type
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Sun, Jing; Mailloux, Brian J; Chillrud, Steven N et al. (2018) Simultaneously Quantifying Ferrihydrite and Goethite in Natural Sediments Using the Method of Standard Additions with X-ray Absorption Spectroscopy. Chem Geol 476:248-259
Argos, Maria; Tong, Lin; Roy, Shantanu et al. (2018) Screening for gene-environment (G×E) interaction using omics data from exposed individuals: an application to gene-arsenic interaction. Mamm Genome 29:101-111
Wu, Fen; Chi, Liang; Ru, Hongyu et al. (2018) Arsenic Exposure from Drinking Water and Urinary Metabolomics: Associations and Long-Term Reproducibility in Bangladesh Adults. Environ Health Perspect 126:017005
Sanchez, Tiffany R; Powers, Martha; Perzanowski, Matthew et al. (2018) A Meta-analysis of Arsenic Exposure and Lung Function: Is There Evidence of Restrictive or Obstructive Lung Disease? Curr Environ Health Rep 5:244-254
Farzan, Shohreh F; Howe, Caitlin G; Chen, Yu et al. (2018) Prenatal lead exposure and elevated blood pressure in children. Environ Int 121:1289-1296
Sanchez, Tiffany R; Slavkovich, Vesna; LoIacono, Nancy et al. (2018) Urinary metals and metal mixtures in Bangladesh: Exploring environmental sources in the Health Effects of Arsenic Longitudinal Study (HEALS). Environ Int 121:852-860
Spratlen, Miranda J; Grau-Perez, Maria; Umans, Jason G et al. (2018) Arsenic, one carbon metabolism and diabetes-related outcomes in the Strong Heart Family Study. Environ Int 121:728-740
Balakrishnan, Poojitha; Navas-Acien, Ana; Haack, Karin et al. (2018) Arsenic-gene interactions and beta-cell function in the Strong Heart Family Study. Toxicol Appl Pharmacol 348:123-129
Oliver-Williams, Clare; Howard, Annie Green; Navas-Acien, Ana et al. (2018) Cadmium body burden, hypertension, and changes in blood pressure over time: results from a prospective cohort study in American Indians. J Am Soc Hypertens 12:426-437.e9
Jones, Miranda R; Tellez-Plaza, Maria; Vaidya, Dhananjay et al. (2018) Ethnic, geographic and dietary differences in arsenic exposure in the multi-ethnic study of atherosclerosis (MESA). J Expo Sci Environ Epidemiol :

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