Public Health Relevance

The carcinogenic and non-carcinogenic mechanisms of action of As are incompletely understood, posing a significant barrier to development of interventions for reducing As-induced diseases. Emerging evidence suggests that As exposure causes epigenetic dysregulation and this is influenced by folate status. Folate may represent simple, low cost, low-risk interventions for prevention of As-induced disease.

Agency
National Institute of Health (NIH)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES010349-13
Application #
8659437
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
Budget End
Support Year
13
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
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