Public Health Relevance

The carcinogenic and non-carcinogenic mechanisms of action of As are incompletely understood, posing a significant barrier to development of interventions for reducing As-induced diseases. Emerging evidence suggests that As exposure causes epigenetic dysregulation and this is influenced by folate status. Folate may represent simple, low cost, low-risk interventions for prevention of As-induced disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES010349-13
Application #
8659437
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
13
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
Kibriya, Muhammad G; Jasmine, Farzana; Parvez, Faruque et al. (2017) Association between genome-wide copy number variation and arsenic-induced skin lesions: a prospective study. Environ Health 16:75
Mateen, Farrah J; Grau-Perez, Maria; Pollak, Jonathan S et al. (2017) Chronic arsenic exposure and risk of carotid artery disease: The Strong Heart Study. Environ Res 157:127-134
Whaley-Martin, K J; Mailloux, B J; van Geen, A et al. (2017) Human and livestock waste as a reduced carbon source contributing to the release of arsenic to shallow Bangladesh groundwater. Sci Total Environ 595:63-71
Chen, Yu; Wu, Fen; Saito, Eiko et al. (2017) Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium. Diabetologia 60:1022-1032
Pfaff, A; Schoenfeld, A; Ahmed, K M et al. (2017) Reduction in exposure to arsenic from drinking well-water in Bangladesh limited by insufficient testing and awareness. J Water Sanit Hyg Dev 7:331-339
Gnanaprakasam, Edwin T; Lloyd, Jonathan R; Boothman, Christopher et al. (2017) Microbial Community Structure and Arsenic Biogeochemistry in Two Arsenic-Impacted Aquifers in Bangladesh. MBio 8:
Zheng, Yan; Flanagan, Sara V (2017) The Case for Universal Screening of Private Well Water Quality in the U.S. and Testing Requirements to Achieve It: Evidence from Arsenic. Environ Health Perspect 125:085002
Keimowitz, Alison R; Mailloux, Brian J; Wovkulich, Karen et al. (2017) Manganese redox buffering limits arsenic release from contaminated sediments, Union Lake, New Jersey. Appl Geochem 77:24-30
Dean, Samantha G; Zhang, Chenan; Gao, Jianjun et al. (2017) The association between telomere length and mortality in Bangladesh. Aging (Albany NY) 9:1537-1551
Radloff, Kathleen A; Zheng, Yan; Stute, Martin et al. (2017) Reversible adsorption and flushing of arsenic in a shallow, Holocene aquifer of Bangladesh. Appl Geochem 77:142-157

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