Public Health Relevance

The carcinogenic and non-carcinogenic mechanisms of action of As are incompletely understood, posing a significant barrier to development of interventions for reducing As-induced diseases. Emerging evidence suggests that As exposure causes epigenetic dysregulation and this is influenced by folate status. Folate may represent simple, low cost, low-risk interventions for prevention of As-induced disease.

Agency
National Institute of Health (NIH)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES010349-13
Application #
8659437
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
Budget End
Support Year
13
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
Flanagan, Sara V; Marvinney, Robert G; Zheng, Yan (2015) Influences on domestic well water testing behavior in a Central Maine area with frequent groundwater arsenic occurrence. Sci Total Environ 505:1274-81
Flanagan, Sara V; Marvinney, Robert G; Johnston, Robert A et al. (2015) Dissemination of well water arsenic results to homeowners in Central Maine: influences on mitigation behavior and continued risks for exposure. Sci Total Environ 505:1282-90
Brocato, Jason; Costa, Max (2015) 10th NTES Conference: Nickel and arsenic compounds alter the epigenome of peripheral blood mononuclear cells. J Trace Elem Med Biol 31:209-13
McClintock, Tyler R; Chen, Yu; Parvez, Faruque et al. (2014) Association between arsenic exposure from drinking water and hematuria: results from the Health Effects of Arsenic Longitudinal Study. Toxicol Appl Pharmacol 276:21-7
Argos, Maria; Tong, Lin; Pierce, Brandon L et al. (2014) Genome-wide association study of smoking behaviours among Bangladeshi adults. J Med Genet 51:327-33
Zheng, Wei; McLerran, Dale F; Rolland, Betsy A et al. (2014) Burden of total and cause-specific mortality related to tobacco smoking among adults aged ? 45 years in Asia: a pooled analysis of 21 cohorts. PLoS Med 11:e1001631
McClintock, Tyler R; Parvez, Faruque; Wu, Fen et al. (2014) Association between betel quid chewing and carotid intima-media thickness in rural Bangladesh. Int J Epidemiol 43:1174-82
Knappett, P S K; Du, J; Liu, P et al. (2014) Importance of Reversible Attachment in Predicting E. Coli Transport in Saturated Aquifers From Column Experiments. Adv Water Resour 63:120-130
Argos, Maria; Parvez, Faruque; Rahman, Mahfuzar et al. (2014) Arsenic and lung disease mortality in Bangladeshi adults. Epidemiology 25:536-43
van Geen, Alexander; Win, Kyi Htut; Zaw, Than et al. (2014) Confirmation of elevated arsenic levels in groundwater of Myanmar. Sci Total Environ 478:21-4

Showing the most recent 10 out of 193 publications