The RTC will enable the CU Center to address issues of high relevance, maximize program investments, and foster innovation while promoting cutting-edge research on the health impacts and geochemistry of Arsenic (As) and Manganese (Mn) via drinking water primarily from groundwater. Our emphasis is on government partnerships, including EPA, ATSDR and local/state agencies managing groundwater drinking water supplies. RTC will work with each Project PI and the Community Engagement Core (CEC) to engage in constructive collaborations with agencies that can benefit from our expertise. The RTC will facilitate interactions with site managers of the Vineland Superfund (SF) site (i.e., EPA, USACE, NJDEP) where CU scientists will work on applying accelerated remediation approaches. With NJDEP, NJGS, USGS and local county DOH partners, we will produce a proof of concept for 3-D risk based maps of As for siting private wells and create educational videos for residents with arsenic in their wells. The RTC and GIS partners at EPA, ATSDR, and NIH will develop and utilize state-of-the art geospatial and analytical tools. Updates to CU SRP online mapping service will identify and analyze the impacts of SF sites on vulnerable populations, to more effectively remediate high priority sites. We will communicate novel findings from our biomedical research to broad audiences via organized forums in the US and Bangladesh. Research translation will be augmented by monthly multidisciplinary seminars, information exchange forums, and targeted meetings. Our EPA partners will announce selected CU SRP seminars via TechDirect (with 37,000+ subscribers) and broadcast them via the online CLU-IN service. We will increase our collaborations with other Centers and SF agencies in planning the SRP Annual Meeting, RTC workshops, Partnership for Environmental Public Health, and other EPA, NIEHS, and ATSDR events. We will inform NIEHS of our Center's research briefs, publications, and success stories on a regular basis via phone, emails, and the online SRP data form. Our own website will be updated on an ongoing basis, profiling CU research &scientists and linking to key resources from EPA, NIEHS, SRP websites and to local issues of interest to the general public.

Public Health Relevance

Research translation can augment and accelerate the impact of basic and applied science on public policies, regulations, and human behavior thereby providing greater protection to the public from adverse exposures to As and Mn in drinking water.

National Institute of Health (NIH)
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
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Columbia University (N.Y.)
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Flanagan, Sara V; Marvinney, Robert G; Zheng, Yan (2015) Influences on domestic well water testing behavior in a Central Maine area with frequent groundwater arsenic occurrence. Sci Total Environ 505:1274-81
Flanagan, Sara V; Marvinney, Robert G; Johnston, Robert A et al. (2015) Dissemination of well water arsenic results to homeowners in Central Maine: influences on mitigation behavior and continued risks for exposure. Sci Total Environ 505:1282-90
Brocato, Jason; Costa, Max (2015) 10th NTES Conference: Nickel and arsenic compounds alter the epigenome of peripheral blood mononuclear cells. J Trace Elem Med Biol 31:209-13
McClintock, Tyler R; Chen, Yu; Parvez, Faruque et al. (2014) Association between arsenic exposure from drinking water and hematuria: results from the Health Effects of Arsenic Longitudinal Study. Toxicol Appl Pharmacol 276:21-7
Argos, Maria; Tong, Lin; Pierce, Brandon L et al. (2014) Genome-wide association study of smoking behaviours among Bangladeshi adults. J Med Genet 51:327-33
Zheng, Wei; McLerran, Dale F; Rolland, Betsy A et al. (2014) Burden of total and cause-specific mortality related to tobacco smoking among adults aged ? 45 years in Asia: a pooled analysis of 21 cohorts. PLoS Med 11:e1001631
McClintock, Tyler R; Parvez, Faruque; Wu, Fen et al. (2014) Association between betel quid chewing and carotid intima-media thickness in rural Bangladesh. Int J Epidemiol 43:1174-82
Knappett, P S K; Du, J; Liu, P et al. (2014) Importance of Reversible Attachment in Predicting E. Coli Transport in Saturated Aquifers From Column Experiments. Adv Water Resour 63:120-130
Argos, Maria; Parvez, Faruque; Rahman, Mahfuzar et al. (2014) Arsenic and lung disease mortality in Bangladeshi adults. Epidemiology 25:536-43
van Geen, Alexander; Win, Kyi Htut; Zaw, Than et al. (2014) Confirmation of elevated arsenic levels in groundwater of Myanmar. Sci Total Environ 478:21-4

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