Today's policymakers must wade through an overwhelming amount of information to establish a knowledge base for decision-making. Thus, good policy outcomes require thoughtful communication of scientific research. Effective translation of Duke SRC research results holds the potential to contribute substantially to the practice of environmental health across NC and nationally. We have three primary audiences for the efforts of the Research Translation Core: (1) scientists at other universities and state and federal agencies (including NIEHS and SRCs at other universities) working on similar questions;(2) environmental health officials and policy makers in state and federal agencies;and (3) community-based groups and non-profits, charged with protecting human health and the environment.
Specific aims for the RTC include: 1) To serve as a bi-directional bridge between the Duke SRC and community groups and other broad-based audiences;2) To communicate with other SRC and NIEHS SRC staff, and national, state, and local environmental health officials regarding the contributions of Center research to contemporary scientific issues;3) To disseminate environmental health research and messages to communities that have traditionally been underserved in outreach and translation efforts, with a particular emphasis on the rapidly growing Hispanic population in North Carolina;4) To use advanced spatial analysis to characterize relationships among contaminants, exposure, and environmental health policy, and then make these results available through the research translation process;and 5)To participate in the transfer of technology from Center investigators to specific end-user audiences. In past years. Center Investigators have contributed significantly to RTC activities, and we are enthusiastic about continuing this collaborative approach. Opportunities for synergy in research translation are created by the SRC's focus on developmental effects from chemical exposure and toxicity and a campus-wide emphasis on the special vulnerabilities of children. This combination will ensure that the full suite of research results emanating from the Duke SRC is available to be communicated to multiple audiences in a timely fashion using tailored formats appropriate to the audience.

Public Health Relevance

The Duke SRC emphasizes the biological costs of early life exposures and remediation strategies throughout all projects and cores. The Research Translation Core will work to ensure that scientific discoveries generated by the SRC will be effectively and widely distributed to the scientific and policy communities, as well as the broader public.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
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Special Emphasis Panel (ZES1-SET-V)
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Duke University
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Oliveri, Anthony N; Ortiz, Erica; Levin, Edward D (2018) Developmental exposure to an organophosphate flame retardant alters later behavioral responses to dopamine antagonism in zebrafish larvae. Neurotoxicol Teratol 67:25-30
Slotkin, Theodore A; Skavicus, Samantha; Seidler, Frederic J (2018) Developmental neurotoxicity resulting from pharmacotherapy of preterm labor, modeled in vitro: Terbutaline and dexamethasone, separately and together. Toxicology 400-401:57-64
Lefèvre, Emilie; Bossa, Nathan; Gardner, Courtney M et al. (2018) Biochar and activated carbon act as promising amendments for promoting the microbial debromination of tetrabromobisphenol A. Water Res 128:102-110
Kollitz, Erin M; Kassotis, Christopher D; Hoffman, Kate et al. (2018) Chemical Mixtures Isolated from House Dust Disrupt Thyroid Receptor ? Signaling. Environ Sci Technol :
Hartman, Jessica H; Smith, Latasha L; Gordon, Kacy L et al. (2018) Swimming Exercise and Transient Food Deprivation in Caenorhabditis elegans Promote Mitochondrial Maintenance and Protect Against Chemical-Induced Mitotoxicity. Sci Rep 8:8359
Luz, Anthony L; Kassotis, Christopher D; Stapleton, Heather M et al. (2018) The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPAR? activation, in 3T3-L1 cells. Toxicology 393:150-159
Day, D B; Xiang, J; Mo, J et al. (2018) Combined use of an electrostatic precipitator and a high-efficiency particulate air filter in building ventilation systems: Effects on cardiorespiratory health indicators in healthy adults. Indoor Air 28:360-372
Slotkin, Theodore A; Ko, Ashley; Seidler, Frederic J (2018) Does growth impairment underlie the adverse effects of dexamethasone on development of noradrenergic systems? Toxicology 408:11-21
Rock, Kylie D; Horman, Brian; Phillips, Allison L et al. (2018) EDC IMPACT: Molecular effects of developmental FM 550 exposure in Wistar rat placenta and fetal forebrain. Endocr Connect 7:305-324
Weinhouse, Caren; Truong, Lisa; Meyer, Joel N et al. (2018) Caenorhabditis elegans as an emerging model system in environmental epigenetics. Environ Mol Mutagen 59:560-575

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