This project is concerned with the factors that determine one aspect of human exposure potentials on contaminated sites. The focus is on vapor inhalation potential. The project involves a combined experimental and modeling study, and has a particular emphasis on mixtures and how these influence the exposure processes. The modeling portion of the study involves further development and validation of a threedimensional computational fluid dynamics model that includes the many variables that can play a role in determining exposures. Earlier models of vapor intrusion have often involved simple one-dimensional descriptions of the phenomenon, and are not adequate for describing the actual situation in the field. Likewise, we are interested in examining transient effects that have been explored to a limited degree in such models.
The aim here is to provide a robust tool, based on a commercial computational platform, that will allow regulators and other concerned parties access to modeling results, permitting more effective guiding of site investigation and remediation efforts. This portion of the program will involve close collaboration with our state agency partners, in providing access to new detailed site characterization information necessary for model validation. At the same time, we will continue an experimental examination of many of the factors that play an important role in determining vapor concentrations in mixed environments. The influence of different parts of the actual soil matrix will also be examined for such systems (e.g., black carbons, humic acids, moisture, other free-phase NAPLs).
Specific Aims of this project: 1. To obtain new experimental data on SVOC mixtures of relevance in vapor exposure scenarios. 2. To continue to develop a robust 3-dimensional model of the vapor intrusion phenomenon, including transient effects, complicated geologies, biodegradation and partitioning. 3. Experimentally explore the partitioning of vapors in the subsurface on black carbon, soil, moisture, NAPL/NAPS as an input to the model in 2 above. 4. Work with state partners to validate the modeling approach with real field data, and make the model available to them as a regulatory tool.
The over-arching goal of this Superfund Basic Research Program is to address health concerns, and to design novel remediation techniques, related to mixed exposures arising from contaminated lands and buildings, using Rhode Island as a model for appropriate research, educational, and training interventions. The choice to focus on vapor intrusion reflects the currently very high level of interest in this phenomenon, and will be important in resolving many of the key scientific questions that have been raised regarding this problem.
|Qiu, Yang; Guo, Fei; Hurt, Robert et al. (2014) Explosive thermal reduction of graphene oxide-based materials: mechanism and safety implications. Carbon N Y 72:215-223|
|Shen, Rui; Suuberg, Eric M (2014) Analytical Quantification of the Subslab Volatile Organic Vapor Concentration from a Non-uniform Source. Environ Model Softw 54:1-8|
|Clift, Danielle; Richendrfer, Holly; Thorn, Robert J et al. (2014) High-throughput analysis of behavior in zebrafish larvae: effects of feeding. Zebrafish 11:455-61|
|Qin, Xiaoli; Liu, Xiaorui; Shan, Bin et al. (2014) Inhibition of eIF5A results in aberrant uterine natural killer cell function and embryo loss in mice. Am J Reprod Immunol 71:229-40|
|Rodd, April L; Creighton, Megan A; Vaslet, Charles A et al. (2014) Effects of surface-engineered nanoparticle-based dispersants for marine oil spills on the model organism Artemia franciscana. Environ Sci Technol 48:6419-27|
|Velazquez-Jimenez, Litza Halla; Hurt, Robert H; Matos, Juan et al. (2014) Zirconium-carbon hybrid sorbent for removal of fluoride from water: oxalic acid mediated Zr(IV) assembly and adsorption mechanism. Environ Sci Technol 48:1166-74|
|Catlin, Natasha R; Huse, Susan M; Boekelheide, Kim (2014) The stage-specific testicular germ cell apoptotic response to low-dose radiation and 2,5-hexanedione combined exposure. II: qRT-PCR array analysis reveals dose dependent adaptive alterations in the apoptotic pathway. Toxicol Pathol 42:1229-37|
|Catlin, Natasha R; Huse, Susan M; Boekelheide, Kim (2014) The stage-specific testicular germ cell apoptotic response to low-dose X-irradiation and 2,5-hexanedione combined exposure. I: Validation of the laser capture microdissection method for qRT-PCR array application. Toxicol Pathol 42:1221-8|
|Shen, Rui; Pennell, Kelly G; Suuberg, Eric M (2014) Analytical modeling of the subsurface volatile organic vapor concentration in vapor intrusion. Chemosphere 95:140-9|
|Sharma, Surendra (2014) Natural killer cells and regulatory T cells in early pregnancy loss. Int J Dev Biol 58:219-29|
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