The primary objective of the Administrative Core (Core A) is to promote, organize and facilitate the crossdisciplinary research activities of the SBRP around environmental health, land re-use and co-exposure issues in Rhode Island. Brown University's SBRP, "REUSE IN RHODE ISLAND: A STATE-BASED APPROACH TO COMPLEX EXPOSURES," began funding in April 2005. The elements that guide us focus on MIXED EXPOSURES, take a STATE-BASED approach to environmental health research, technology development, and contaminated land re-use with RHODE ISLAND as our laboratory. During our initial three years of funding, we have established ourselves as an innovative program of intellectual activity and of basic research and applied science at Brown and throughout Rhode Island. Our newly established Center for Environmental Health and Technology (CEHT), officially recognized by the Brown University Corporation in Spring, 2007, has strengthened the identity, status and capabilities of our SBRP. CEHT provides a structure for expanding our research and core activities, and facilitates collaboration with other programs within Brown University, and with community and government agencies within the State of Rhode Island.
The Specific Aims of our SBRP include:
Specific Aim 1 : Develop processes that support and accommodate the growth of the interdisciplinary basic and applied research and training.
Specific Aim 2 : Maintain a communication structure that strengthens team building and facilitates the dissemination of information.
Specific Aim 3 : Implement mechanisms that will optimally promote the program's objectives and ensure the best and responsible use of the available resources.

Public Health Relevance

The over-arching goal of this Superfund Basic Research Program is to address health concerns, and to design novel remediation techniques, related to mixed exposures arising from contaminated lands and buildings, using Rhode Island as a model for appropriate research, educational, and training interventions. The Administrative Core functions as the organizational and communication center of the Brown SBRP.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES013660-09
Application #
8451581
Study Section
Special Emphasis Panel (ZES1-LKB-D)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
9
Fiscal Year
2013
Total Cost
$167,322
Indirect Cost
$71,506
Name
Brown University
Department
Type
DUNS #
001785542
City
Providence
State
RI
Country
United States
Zip Code
02912
Zhu, Wenpeng; von dem Bussche, Annette; Yi, Xin et al. (2016) Nanomechanical mechanism for lipid bilayer damage induced by carbon nanotubes confined in intracellular vesicles. Proc Natl Acad Sci U S A 113:12374-12379
Dere, Edward; Wilson, Shelby K; Anderson, Linnea M et al. (2016) From the Cover: Sperm Molecular Biomarkers Are Sensitive Indicators of Testicular Injury following Subchronic Model Toxicant Exposure. Toxicol Sci 153:327-40
Gonzalez, Sarah T; Remick, Dylan; Creton, Robbert et al. (2016) Effects of embryonic exposure to polychlorinated biphenyls (PCBs) on anxiety-related behaviors in larval zebrafish. Neurotoxicology 53:93-101
Pennell, Kelly G; Scammell, Madeleine K; McClean, Michael D et al. (2016) Field data and numerical modeling: A multiple lines of evidence approach for assessing vapor intrusion exposure risks. Sci Total Environ 556:291-301
Verginelli, Iason; Yao, Yijun; Wang, Yue et al. (2016) Estimating the oxygenated zone beneath building foundations for petroleum vapor intrusion assessment. J Hazard Mater 312:84-96
Lovato, Ava K; Creton, Robbert; Colwill, Ruth M (2016) Effects of embryonic exposure to polychlorinated biphenyls (PCBs) on larval zebrafish behavior. Neurotoxicol Teratol 53:1-10
Kuempel, Eileen D; Jaurand, Marie-Claude; Møller, Peter et al. (2016) Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans. Crit Rev Toxicol :1-58
Holden, Patricia A; Gardea-Torresdey, Jorge L; Klaessig, Fred et al. (2016) Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazards of Engineered Nanomaterials. Environ Sci Technol 50:6124-45
Dere, E; Huse, S; Hwang, K et al. (2016) Intra- and inter-individual differences in human sperm DNA methylation. Andrology 4:832-42
Wang, Zhongying; Zhu, Wenpeng; Qiu, Yang et al. (2016) Biological and environmental interactions of emerging two-dimensional nanomaterials. Chem Soc Rev 45:1750-80

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