The Administrative Core promotes intellectual activities, organization of venues for planning future research through seminars and retreats, and oversight of research and spending. This Core also provides the tools to work with institutions inside and outside of Harvard School of Public Health to leverage the potential of the Superfund Basic Research Program to translate the findings of our research and to promote research on mixtures, gene-environment interactions, and the movement of metals in the environment.
The specific aims of the Administrative Core are to:
Aim 1. Research. To monitor research progress, coordinate Internal Advisory Committee (Governance Committee) meetings, and foster collaborative research both within the SBRP Program and among other Harvard affiliated institutions and collaborative institutions, such as MIT Aim 2. Communication. To foster communication between the Harvard SBRP and SBRP programs within EPA Region 1 (Dartmouth, Brown, Boston University) and agencies such as EPA, ATSDR and the Pediatric Environmental Health Subspecialty Units (PEHSUs), and to maintain close communication with the National Institute of Environmental Health Sciences Aim 3. To provide necessary resources and fiscal oversight Aim 4. To promote rapid dissemination of significant research findings Aim 5. Compliance. To ensure compliance with NIH requirements for data and resource-sharing and the human and animal institutional review board requirements

Public Health Relevance

Core A, under Dr. Wright, will provide scientific leadership, insuring coordination and integration among projects and cores. Core A will provide administrative leadership directing the administration of research funds and maintaining compliance with all relevant federal regulations.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
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Special Emphasis Panel (ZES1-LWJ-M)
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Burris, Heather H; Baccarelli, Andrea A; Motta, Valeria et al. (2014) Association between length of gestation and cervical DNA methylation of PTGER2 and LINE 1-HS. Epigenetics 9:1083-91
Kile, Molly L; Rodrigues, Ema G; Mazumdar, Maitreyi et al. (2014) A prospective cohort study of the association between drinking water arsenic exposure and self-reported maternal health symptoms during pregnancy in Bangladesh. Environ Health 13:29
Claus Henn, Birgit; Coull, Brent A; Wright, Robert O (2014) Chemical mixtures and children's health. Curr Opin Pediatr 26:223-9
Kile, Molly L; Houseman, E Andres; Baccarelli, Andrea A et al. (2014) Effect of prenatal arsenic exposure on DNA methylation and leukocyte subpopulations in cord blood. Epigenetics 9:774-82
Gleason, Kelsey; Shine, James P; Shobnam, Nadia et al. (2014) Contaminated turmeric is a potential source of lead exposure for children in rural Bangladesh. J Environ Public Health 2014:730636
Karwowski, Mateusz P; Just, Allan C; Bellinger, David C et al. (2014) Maternal iron metabolism gene variants modify umbilical cord blood lead levels by gene-environment interaction: a birth cohort study. Environ Health 13:77
Braun, Joseph M; Wright, Rosalind J; Just, Allan C et al. (2014) Relationships between lead biomarkers and diurnal salivary cortisol indices in pregnant women from Mexico City: a cross-sectional study. Environ Health 13:50
Fossati, Serena; Baccarelli, Andrea; Zanobetti, Antonella et al. (2014) Ambient particulate air pollution and microRNAs in elderly men. Epidemiology 25:68-78
Lee, Seunggeung; Abecasis, Gonçalo R; Boehnke, Michael et al. (2014) Rare-variant association analysis: study designs and statistical tests. Am J Hum Genet 95:5-23
Orenstein, Sara T C; Thurston, Sally W; Bellinger, David C et al. (2014) Prenatal organochlorine and methylmercury exposure and memory and learning in school-age children in communities near the New Bedford Harbor Superfund site, Massachusetts. Environ Health Perspect 122:1253-9

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