Community Outreach Core: Tribal-University Collaboration to Address Tribal Exposures to PAHs and Improve Community Health. The goal of the Community Outreach Core is to apply the knowledge gained from our SBRP to better understand health risks associated with PAH exposure on the Umatilla Indian Reservation and to assist in human capacity building with Tribal partners. This will be accomplished through a collaborative project that includes the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) Tribal agencies, Tribal and University investigators, and Tribal community members. The CTUIR and many other U.S. Tribes are engaged in traditional and cultural practices that may result in increased risk of disease due to cumulative PAH exposures from traditionally-smoked foods, air exposure from traditional smoking of foods, and ambient air pollution. Tribal members cannot give up their culture and religion or move from their homelands in order to avoid contaminants. Thus, it is critically important for them to develop the capacity to better understand the nature of these exposures, and to be engaged in the development and communication of culturally appropriate and practical risk reduction strategies.
The specific aims of the Outreach Core are to: 1) establish and convene an interdisciplinary advisory group representing Tribal and government agencies, and other members who will add additional expertise in tribal cultural lifestyles and culturally-appropriate risk reduction measures;2) engage in human capacity building with the Umatilla Tribal partners and identify opportunities to better assess PAH exposure pathways specific and relevant to their traditional and cultural practices;3) develop culturally appropriate risk reduction approaches and outreach strategies that offer the best opportunity for improved health. This Outreach Core builds on strengths and resources within the Tribal community, and will facilitative a collaborative, equitable partnership in all phases of the project. Direct capacity building activities will be carried out with the CTUIR Department of Science and Engineering, and will be informed by an interdisciplinary advisory group representing tribal entities. The approach that evolves from this Core will serve as a model to help other Tribal communities evaluate their PAH exposures and design risk reduction strategies that are protective of public health.
|Knecht, Andrea L; Truong, Lisa; Simonich, Michael T et al. (2016) Developmental benzo[a]pyrene (B[a]P) exposure impacts larval behavior and impairs adult learning in zebrafish. Neurotoxicol Teratol :|
|Bugel, Sean M; Wehmas, Leah C; La Du, Jane K et al. (2016) Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium. Toxicol Appl Pharmacol 296:31-41|
|Sadler, Natalie C; Nandhikonda, Premchendar; Webb-Robertson, Bobbie-Jo et al. (2016) Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development. Drug Metab Dispos 44:984-91|
|Haggard, Derik E; Noyes, Pamela D; Waters, Katrina M et al. (2016) Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish. Toxicol Appl Pharmacol 308:32-45|
|Bugel, Sean M; Bonventre, Josephine A; Tanguay, Robert L (2016) Comparative Developmental Toxicity of Flavonoids Using an Integrative Zebrafish System. Toxicol Sci 154:55-68|
|Paulik, L Blair; Smith, Brian W; Bergmann, Alan J et al. (2016) Passive samplers accurately predict PAH levels in resident crayfish. Sci Total Environ 544:782-91|
|Tidwell, Lane G; Allan, Sarah E; O'Connell, Steven G et al. (2016) PAH and OPAH Flux during the Deepwater Horizon Incident. Environ Sci Technol 50:7489-97|
|Garcia, Gloria R; Noyes, Pamela D; Tanguay, Robert L (2016) Advancements in zebrafish applications for 21st century toxicology. Pharmacol Ther 161:11-21|
|Zhang, Guozhu; Roell, Kyle R; Truong, Lisa et al. (2016) A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades. Toxicol Appl Pharmacol 314:109-117|
|Truong, Lisa; Bugel, Sean M; Chlebowski, Anna et al. (2016) Optimizing multi-dimensional high throughput screening using zebrafish. Reprod Toxicol 65:139-147|
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