Community Outreach Core: Tribal-University Collaboration to Address Tribal Exposures to PAHs and Improve Community Health. The goal of the Community Outreach Core is to apply the knowledge gained from our SBRP to better understand health risks associated with PAH exposure on the Umatilla Indian Reservation and to assist in human capacity building with Tribal partners. This will be accomplished through a collaborative project that includes the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) Tribal agencies, Tribal and University investigators, and Tribal community members. The CTUIR and many other U.S. Tribes are engaged in traditional and cultural practices that may result in increased risk of disease due to cumulative PAH exposures from traditionally-smoked foods, air exposure from traditional smoking of foods, and ambient air pollution. Tribal members cannot give up their culture and religion or move from their homelands in order to avoid contaminants. Thus, it is critically important for them to develop the capacity to better understand the nature of these exposures, and to be engaged in the development and communication of culturally appropriate and practical risk reduction strategies.
The specific aims of the Outreach Core are to: 1) establish and convene an interdisciplinary advisory group representing Tribal and government agencies, and other members who will add additional expertise in tribal cultural lifestyles and culturally-appropriate risk reduction measures;2) engage in human capacity building with the Umatilla Tribal partners and identify opportunities to better assess PAH exposure pathways specific and relevant to their traditional and cultural practices;3) develop culturally appropriate risk reduction approaches and outreach strategies that offer the best opportunity for improved health. This Outreach Core builds on strengths and resources within the Tribal community, and will facilitative a collaborative, equitable partnership in all phases of the project. Direct capacity building activities will be carried out with the CTUIR Department of Science and Engineering, and will be informed by an interdisciplinary advisory group representing tribal entities. The approach that evolves from this Core will serve as a model to help other Tribal communities evaluate their PAH exposures and design risk reduction strategies that are protective of public health.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES016465-04
Application #
8375931
Study Section
Special Emphasis Panel (ZES1-LKB-D)
Project Start
Project End
2013-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
4
Fiscal Year
2012
Total Cost
$133,470
Indirect Cost
$41,793
Name
Oregon State University
Department
Type
DUNS #
053599908
City
Corvallis
State
OR
Country
United States
Zip Code
97339
Garcia, Gloria R; Goodale, Britton C; Wiley, Michelle W et al. (2017) In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression. Mol Pharmacol 91:609-619
Donald, Carey E; Anderson, Kim A (2017) Assessing soil-air partitioning of PAHs and PCBs with a new fugacity passive sampler. Sci Total Environ 596-597:293-302
Wittwehr, Clemens; Aladjov, Hristo; Ankley, Gerald et al. (2017) How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology. Toxicol Sci 155:326-336
Madeen, Erin P; Williams, David E (2017) Environmental PAH exposure and male idiopathic infertility: a review on early life exposures and adult diagnosis. Rev Environ Health 32:73-81
Shrivastava, Manish; Lou, Silja; Zelenyuk, Alla et al. (2017) Global long-range transport and lung cancer risk from polycyclic aromatic hydrocarbons shielded by coatings of organic aerosol. Proc Natl Acad Sci U S A 114:1246-1251
Geier, Mitra C; Chlebowski, Anna C; Truong, Lisa et al. (2017) Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons. Arch Toxicol :
Knecht, Andrea L; Truong, Lisa; Simonich, Michael T et al. (2017) Developmental benzo[a]pyrene (B[a]P) exposure impacts larval behavior and impairs adult learning in zebrafish. Neurotoxicol Teratol 59:27-34
Zhang, Guozhu; Truong, Lisa; Tanguay, Robert L et al. (2017) A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish. PLoS One 12:e0169408
Madeen, Erin P; Löhr, Christiane V; You, Hannah et al. (2017) Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. Mol Carcinog 56:163-171
Knecht, Andrea L; Truong, Lisa; Marvel, Skylar W et al. (2017) Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish. Toxicol Appl Pharmacol 329:148-157

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