The Administrative Core is responsible for defining the mission of the Oregon State University SRP, ensuring the paths to pursue that mission are clearly communicated within and without the SRP, providing our investigators with necessary tools to achieve those goals, developing a long-term vision to meet stakeholder needs and fill in missing gaps in the science required to make the most informed regulatory decisions possible. Our Core continues to be innovative and engaged. Our organization is unique among SRPs in that we employ an Internal Advisory Committee (lAC) of key administrators, established the position of Research Coordinator and formed a partnership with a National Laboratory. The lAC was instrumental in obtaining strong institutional support and the Research Coordinator proved a powerful conduit between projects and cores, acting as a """"""""catalyst"""""""". We were able to """"""""hit the ground running"""""""" as a new SRP due to a long history of the Administrative Core staff in managing multi-disciplinary, multi-investigator extramural programs and institutional Centers. A key component of our success to date has been our engaged External Advisory Committee (EAC), formed two years before we were funded. The EAC was active in our initial proposal, pursuit of our mission over this funding period and developing our vision for this competing renewal. As we move forward our leadership team has sharpened our vision resulting in elimination of 1 project and substantial re-organization of 2 others. Oregon State University officially recognized our group as an institutional Center which enhances our visibility, ensures centralized monetary support and provides for control of a significant portion of indirect funds generated by this grant. This has allowed us to make important investments in our early development years and to rapidly respond to events such as the Deepwater Horizon spill. We now are positioned as leaders in the field of polycyclic aromatic hydrocarbons (PAHs). PAHs are not only found at Superfund Sites, but often are the main driver for risk assessment and remediation. We continue to develop new technologies and innovative approaches for studying PAHs. The Administrative Core is poised to not just manager but act as a guide as we pursue our NIEHS-SRP mission.

Public Health Relevance

The Administrative Core is the heart of an SRP;it is also the face. Its actions are critical to how the efforts of the investigators are seen regionally, nationally and even internationally. Responsibilities of the AC go beyond good management but require innovation and long-term vision in order to contribute to filling in knowledge and technology gaps needed by stakeholders to address issues critical to Superfund sites.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES016465-06
Application #
8695370
Study Section
Special Emphasis Panel ()
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
6
Fiscal Year
2014
Total Cost
$73,257
Indirect Cost
$12,053
Name
Oregon State University
Department
Type
DUNS #
053599908
City
Corvallis
State
OR
Country
United States
Zip Code
97339
Garcia, Gloria R; Goodale, Britton C; Wiley, Michelle W et al. (2017) In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression. Mol Pharmacol 91:609-619
Donald, Carey E; Anderson, Kim A (2017) Assessing soil-air partitioning of PAHs and PCBs with a new fugacity passive sampler. Sci Total Environ 596-597:293-302
Wittwehr, Clemens; Aladjov, Hristo; Ankley, Gerald et al. (2017) How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology. Toxicol Sci 155:326-336
Madeen, Erin P; Williams, David E (2017) Environmental PAH exposure and male idiopathic infertility: a review on early life exposures and adult diagnosis. Rev Environ Health 32:73-81
Shrivastava, Manish; Lou, Silja; Zelenyuk, Alla et al. (2017) Global long-range transport and lung cancer risk from polycyclic aromatic hydrocarbons shielded by coatings of organic aerosol. Proc Natl Acad Sci U S A 114:1246-1251
Geier, Mitra C; Chlebowski, Anna C; Truong, Lisa et al. (2017) Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons. Arch Toxicol :
Knecht, Andrea L; Truong, Lisa; Simonich, Michael T et al. (2017) Developmental benzo[a]pyrene (B[a]P) exposure impacts larval behavior and impairs adult learning in zebrafish. Neurotoxicol Teratol 59:27-34
Zhang, Guozhu; Truong, Lisa; Tanguay, Robert L et al. (2017) A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish. PLoS One 12:e0169408
Madeen, Erin P; Löhr, Christiane V; You, Hannah et al. (2017) Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. Mol Carcinog 56:163-171
Knecht, Andrea L; Truong, Lisa; Marvel, Skylar W et al. (2017) Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish. Toxicol Appl Pharmacol 329:148-157

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