Community Engagement Core: Tribal-University Evaluation of Chemical Exposures to Improve Community Health The Community Engagement Core will facilitate collaborations among OSU researchers and Native American Tribes in the Pacific Northwest to address Tribal concerns regarding exposure to chemicals in their environment, with a focus on understanding exposure pathways to polycyclic aromatic hydrocarbons (PAHs). Our community partners are the Confederated Tribes of the Umatilla Indian Reservation (CTUIR), the Swinomish Indian Tribal Community, and the Samish Indian Nation. Tribal communities experience exposure to PAHs and many chemicals on the CERCLA priority list from diverse sources: they reside on reservations impacted by hazardous waste sites, they collect subsistence foods from contaminated waterways, and they gather traditional foods from contaminated lands. Housing characteristics and traditional practices such as smoking foods also contribute to their chemical exposures. The cumulative exposures from these unique pathways may increase the risk of environmentally-related disease. It is critically important that Tribal communities understand these exposures and develop culturally appropriate responses and risk reduction strategies because they cannot move from their homelands to avoid contaminants and they cannot give up their culture or their religion. In turn, the research community must develop the cultural capacity to work with Tribal communities according to the principles of community-based research.
The specific aims of the Community Engagement Core are to: 1) address CTUIR concerns regarding their environmental exposures, build Tribal capacity to measure environmental pollutants, and develop risk reduction strategies that will improve health without adversely affecting cultural practices;2) build tribal capacity in analytical methods used by the CTUIR and help both the Swinomish Tribal Indian Community and the Samish Indian Nation to improve their understanding of PAH and other chemical exposures;3) collaborate with other SRP Centers, EPA regional offices, the Agency for Toxic Substances and Disease, the Office of Tribal Affairs, and other stakeholders to disseminate our research findings and the principles of community-based environmental health research with tribal populations that reside on contaminated lands.

Public Health Relevance

Core E will build scientific capacity in Tribal communities and cultural capacity within the research community. We will improve risk assessment models by accounting for tribal land-use scenarios and unique exposure pathways. By translating this knowledge into effective and appropriate risk reduction strategies, we will reduce environmental disparities and improve the health of Pacific Northwest Tribes.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES016465-06
Application #
8695372
Study Section
Special Emphasis Panel ()
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
6
Fiscal Year
2014
Total Cost
$127,457
Indirect Cost
$40,157
Name
Oregon State University
Department
Type
DUNS #
053599908
City
Corvallis
State
OR
Country
United States
Zip Code
97339
Balik-Meisner, Michele; Truong, Lisa; Scholl, Elizabeth H et al. (2018) Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure. Environ Health Perspect 126:067010
Geier, Mitra C; James Minick, D; Truong, Lisa et al. (2018) Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish. Toxicol Appl Pharmacol 354:115-125
Tan, Yu-Mei; Leonard, Jeremy A; Edwards, Stephen et al. (2018) Aggregate Exposure Pathways in Support of Risk Assessment. Curr Opin Toxicol 9:8-13
Titaley, Ivan A; Ogba, O Maduka; Chibwe, Leah et al. (2018) Automating data analysis for two-dimensional gas chromatography/time-of-flight mass spectrometry non-targeted analysis of comparative samples. J Chromatogr A 1541:57-62
Geier, Mitra C; Chlebowski, Anna C; Truong, Lisa et al. (2018) Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons. Arch Toxicol 92:571-586
Bugel, Sean M; Tanguay, Robert L (2018) Multidimensional chemobehavior analysis of flavonoids and neuroactive compounds in zebrafish. Toxicol Appl Pharmacol 344:23-34
Garcia, Gloria R; Bugel, Sean M; Truong, Lisa et al. (2018) AHR2 required for normal behavioral responses and proper development of the skeletal and reproductive systems in zebrafish. PLoS One 13:e0193484
Roper, Courtney; Simonich, Staci L Massey; Tanguay, Robert L (2018) Development of a high-throughput in vivo screening platform for particulate matter exposures. Environ Pollut 235:993-1005
Haggard, Derik E; Noyes, Pamela D; Waters, Katrina M et al. (2018) Transcriptomic and phenotypic profiling in developing zebrafish exposed to thyroid hormone receptor agonists. Reprod Toxicol 77:80-93
Hummel, Jessica M; Madeen, Erin P; Siddens, Lisbeth K et al. (2018) Pharmacokinetics of [14C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction. Food Chem Toxicol 115:136-147

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