PROJECT SUMIVIARY (See instructions): The OSU SRP Training Core focuses on providing synergistic opportunities for graduate students, postdoctoral fellows, staff and newly hired faculty to develop the types of trans-disciplinary skill sets needed to address the challenges posed by the Superfund Program. We will train a new generation of transdisciplinaty scientists to address critical, complex problems of hazard assessment, environmental monitoring, and human health risk assessment for complex PAH mixtures and other contaminants present at Superfund Sites. The Training Core will specifically provide advanced pre- and post-doctoral training in PAH analysis, pharmacokinetics, systems-level toxicology, and risk assessment through the novel use of discoveries and new technologies emerging from our SRP research programs and support cores. An integrated educational experience that is focused on Superfund relevant issues will be constructed from individualized biomedical and non-biomedical didactic training combined with experiential learning opportunities that address SRP relevant issues. Such an approach will be complimented with both formal and informal opportunities for trainees in science communication and outreach activities. A distinctive aspect of our Training Core involves regional collaborations between Pacific Northwest SRPs (OSU, UC Davis and U. Washington) to substantially broaden the scope of SRP training experience through both shared and complimentaty training activities at each Center's Research Translation and Community Engagement Cores. Our training program will provide experiential opportunities in commercial, public health and regulatoty environments in addition to the traditional academic venues through innovative training partnerships with private risk-assessment firms, regulatoty agencies (EPA Region 10) and a local ecotoxicology contract laboratory generating data for commercial and government regulatory entities. Our trans-disciplinary program will prepare trainees to better understand the broad and complex challenges under investigation in our SRP during their tenure at OSU, as well as position the trainees for future careers in academic, industrial and environmental regulatory positions addressing Superfund issues.
This training program will help synergize ongoing research projects at OSU and at other Superfund Research Programs and matriculate individuals with the highly integrated and trans-disciplinary skill sets able to work at the interface between traditional fields and nucleate interdisciplinary collaborative studies to solve complex environmental problems.
|Madeen, Erin; Corley, Richard A; Crowell, Susan et al. (2015) Human in Vivo Pharmacokinetics of [(14)C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Microdosing. Chem Res Toxicol 28:126-34|
|O'Connell, Steven G; Kincl, Laurel D; Anderson, Kim A (2014) Silicone wristbands as personal passive samplers. Environ Sci Technol 48:3327-35|
|O'Connell, Steven G; McCartney, Melissa A; Paulik, L Blair et al. (2014) Improvements in pollutant monitoring: optimizing silicone for co-deployment with polyethylene passive sampling devices. Environ Pollut 193:71-8|
|Kile, Molly L; Coker, Eric S; Smit, Ellen et al. (2014) A cross-sectional study of the association between ventilation of gas stoves and chronic respiratory illness in U.S. children enrolled in NHANESIII. Environ Health 13:71|
|Crowell, S R; Hanson-Drury, S; Williams, D E et al. (2014) In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes. Toxicol Lett 228:48-55|
|Jariyasopit, Narumol; Zimmermann, Kathryn; Schrlau, Jill et al. (2014) Heterogeneous reactions of particulate matter-bound PAHs and NPAHs with NO3/N2O5, OH radicals, and O3 under simulated long-range atmospheric transport conditions: reactivity and mutagenicity. Environ Sci Technol 48:10155-64|
|Forsberg, Norman D; O'Connell, Steven G; Allan, Sarah E et al. (2014) Passive sampling coupled to ultraviolet irradiation: a useful analytical approach for studying oxygenated polycyclic aromatic hydrocarbon formation in bioavailable mixtures. Environ Toxicol Chem 33:177-81|
|Hillwalker, Wendy E; Anderson, Kim A (2014) Bioaccessibility of metals in alloys: evaluation of three surrogate biofluids. Environ Pollut 185:52-8|
|Jariyasopit, Narumol; McIntosh, Melissa; Zimmermann, Kathryn et al. (2014) Novel nitro-PAH formation from heterogeneous reactions of PAHs with NO2, NO3/N2O5, and OH radicals: prediction, laboratory studies, and mutagenicity. Environ Sci Technol 48:412-9|
|Bugel, Sean M; Bonventre, Josephine A; White, Lori A et al. (2014) Chronic exposure of killifish to a highly polluted environment desensitizes estrogen-responsive reproductive and biomarker genes. Aquat Toxicol 152:222-31|
Showing the most recent 10 out of 61 publications