The PROTECT (Puerto Rico Testsite for Exploring Contamination Threats) Center includes five research projects, two research support cores and four required enrichment cores, one of which is the Administrative Core. The primary objective of the Administrative Core is to provide a formal structure for oversight, planning, coordination, and promotion of cross-disciplinary, multi-university interaction by projects and cores.
The specific aims of the Administrative Core are to (1) provide center leadership and coordination;(2) facilitate and ensure integration of cross-disciplinary, multi-university activities;(3) provide fiscal management and administrative services and monitor resources and expenditures;(4) maintain smooth interaction with external advisory committee members and active communication with the NIEHS, EPA and SRP;(5) provide center documentation, reporting and assessment;and (6) promote PROTECT activities among the participating institutions, government and industry. Managing a geographically distributed, multi-university team requires a sophisticated administrative structure. Substantial planning, organization, and effective communications tools promote active collaboration and coordination. To this end, the Administrative Core developed a framework that links projects, institutions and participants. This includes highly-qualified and experienced Center Directors who manage and guide PROTECT research, training and stakeholder engagement activities;an Executive Committee to manage, facilitate and monitor the technical quality of projects and cores;and a dedicated Administrative Staff who support PROTECT research and administrative activities using appropriate information technology, financial and reporting software and communications tools. To advise and guide the effort;an External Advisory Committee was formed with five subcommittees focused on important issues, i.e. the Scientific Advisory Committee assesses research merit, cross-disciplinary integration, translation and relevance;the Institutional Partnership Advisory Committee provides necessary institutional-level guidance and promotes long-range strategic goals;and Research Translation, Training, and Community Engagement Advisory Committees support their respective cores. Frequent, routine management and coordination/integration meetings are planned for optimal participation by PROTECT personnel and advisors. This effective strategy was used during the first three years of PROTECT, resulting in collaboration and integration across projects, cores and institutions, successful communication with advisory committees, and timely, accurate financial tracking and progress reporting to NIEHS/SRP.

Public Health Relevance

The Administrative Core provides a formal structure for oversight, planning, coordination, and promotion of cross-disciplinary interaction among all of the projects, cores, and participating institutions. The leadership and guidance provided by the Administrative Core is necessary to fulfill the ultimate goal of PROTECT: to understand the impact of environmental contamination on preterm birth in Puerto Rico and beyond.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
2P42ES017198-05
Application #
8649389
Study Section
Special Emphasis Panel (ZES1-LKB-K (S))
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
5
Fiscal Year
2014
Total Cost
$192,590
Indirect Cost
$68,738
Name
Northeastern University
Department
Type
DUNS #
001423631
City
Boston
State
MA
Country
United States
Zip Code
02115
Ferguson, Kelly K; Colacino, Justin A; Lewis, Ryan C et al. (2017) Personal care product use among adults in NHANES: associations between urinary phthalate metabolites and phenols and use of mouthwash and sunscreen. J Expo Sci Environ Epidemiol 27:326-332
Elkin, Elana R; O'Neill, Marie S (2017) Trends in Environmental Tobacco Smoke (ETS) Exposure and Preterm Birth: Use of Smoking Bans and Direct ETS Exposure Assessments in Study Designs. Chem Res Toxicol 30:1376-1383
Ferguson, Kelly K; McElrath, Thomas F; Pace, Gerry G et al. (2017) Urinary Polycyclic Aromatic Hydrocarbon Metabolite Associations with Biomarkers of Inflammation, Angiogenesis, and Oxidative Stress in Pregnant Women. Environ Sci Technol 51:4652-4660
Park, Hae-Ryung; Harris, Sean M; Boldenow, Erica et al. (2017) Group B Streptococcus Activates Transcriptomic Pathways Related to Premature Birth in Human Extraplacental Membranes In Vitro. Biol Reprod :
Ferguson, Kelly K; Meeker, John D; Cantonwine, David E et al. (2017) Environmental phenol associations with ultrasound and delivery measures of fetal growth. Environ Int 112:243-250
Shao, Gang; Agar, Jeffrey; Giese, Roger W (2017) Cold-induced aqueous acetonitrile phase separation: A salt-free way to begin quick, easy, cheap, effective, rugged, safe. J Chromatogr A 1506:128-133
Wang, Poguang; Giese, Roger W (2017) Recommendations for quantitative analysis of small molecules by matrix-assisted laser desorption ionization mass spectrometry. J Chromatogr A 1486:35-41
Ferguson, Kelly K; Chen, Yin-Hsiu; VanderWeele, Tyler J et al. (2017) Mediation of the Relationship between Maternal Phthalate Exposure and Preterm Birth by Oxidative Stress with Repeated Measurements across Pregnancy. Environ Health Perspect 125:488-494
Aung, Max T; Johns, Lauren E; Ferguson, Kelly K et al. (2017) Thyroid hormone parameters during pregnancy in relation to urinary bisphenol A concentrations: A repeated measures study. Environ Int 104:33-40
Yuan, Ye; Meeker, John D; Ferguson, Kelly K (2017) Serum polybrominated diphenyl ether (PBDE) concentrations in relation to biomarkers of oxidative stress and inflammation: The National Health and Nutrition Examination Survey 2003-2004. Sci Total Environ 575:400-405

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