The Puerto Rico Testsite for Exploring Contamination Threats Center (PROTECT) uses an integrated, cross- disciplinary approach to study the fate, transport, exposure, health impact and remediation of contaminants commonly found at Superfund sites, with particular attention to phthalates and chlorinated solvents as both are suspect and model agents in the high preterm birth rates in Puerto Rico. The Research Translation Core (RTC) serves the overall interests of PROTECT and NIEHS by translating and disseminating PROTECT research results to a wide variety of governmental agencies, scientific communities, industry, and other stakeholders. The RTC does this through five aims: ? Aim 1: Publicize and emphasize to EPA, ATSDR, and other stakeholders the significance and/or relevance of program findings for public policy, public health, and prevention ? Aim 2: Build partnerships with stakeholders to respond to requests, develop capacity, and improve understanding of Center findings ? Aim 3: Serve as the bridge between investigators, partners and stakeholders to foster commercial development, utilization and translation of the knowledge gained by the SRP program into tools, strategies or technologies, in an efficient and timely manner ? Aim 4: Collaborate with other PROTECT cores for enhanced sharing of information, materials and best practices outside of PROTECT ? Aim 5: Communicate PROTECT work to SRP Headquarters and to the national SRP community These aims are realized through activities that solidify internal communications within PROTECT, communications with other SRPs and the national office, and communication with a wide range of professional, governmental, public health, and community organizations. The RTC works with each project leader to develop translational activities, and it offers training sessions for faculty, postdocs, and students to facilitate research translation. The RTC develops mechanisms for technology transfer, such as patents, commercialization, and intellectual property. It facilitates consultations of expertise and new collaborations, particularly outside the SRP community. The RTC helps investigators to increase NIEHS and other grant submissions, thus expanding the environmental health capacity of the constituent campuses. It offers webinars and conferences to share findings and for communities to share experiences/needs with the university researchers, especially by collaborating with the Training Core and Community Engagement Core. The RTC has a strong website presence and is the central clearinghouse for collating and disseminating PROTECT results and materials. The RTC also develops publications that highlight the overall sum of PROTECT's research translation outcomes.

Public Health Relevance

PROTECT uses an integrated, cross-disciplinary approach to study the transport, exposure, health impact and remediation of contaminants commonly found at Superfund sites, with particular attention to phthalates and chlorinated solvents as both are suspect in the high preterm birth rates in Puerto Rico. The Research Translation Core coordinates PROTECT's efforts to translate and disseminate research results from all Center projects to stakeholders, to promote understanding of contaminant exposure and assist in public health education and intervention.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
2P42ES017198-05
Application #
8649390
Study Section
Special Emphasis Panel (ZES1-LKB-K (S))
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
5
Fiscal Year
2014
Total Cost
$123,887
Indirect Cost
$44,217
Name
Northeastern University
Department
Type
DUNS #
001423631
City
Boston
State
MA
Country
United States
Zip Code
02115
Nazari, Roya; Raji?, Ljiljana; Xue, Yunfei et al. (2018) Degradation of 4-Chlorophenol in Aqueous Solution by Sono-Electro-Fenton Process. Int J Electrochem Sci 13:9214-9230
Zhou, Wei; Meng, Xiaoxiao; Rajic, Ljiljana et al. (2018) ""Floating"" cathode for efficient H2O2 electrogeneration applied to degradation of ibuprofen as a model pollutant. Electrochem commun 96:37-41
Ashrap, Pahriya; Watkins, Deborah J; Calafat, Antonia M et al. (2018) Elevated concentrations of urinary triclocarban, phenol and paraben among pregnant women in Northern Puerto Rico: Predictors and trends. Environ Int 121:990-1002
Ferguson, Kelly K; Meeker, John D; Cantonwine, David E et al. (2018) Environmental phenol associations with ultrasound and delivery measures of fetal growth. Environ Int 112:243-250
Cathey, Amber; Ferguson, Kelly K; McElrath, Thomas F et al. (2018) Distribution and predictors of urinary polycyclic aromatic hydrocarbon metabolites in two pregnancy cohort studies. Environ Pollut 232:556-562
Lan, Jiaqi; Rahman, Sheikh Mokhlesur; Gou, Na et al. (2018) Genotoxicity Assessment of Drinking Water Disinfection Byproducts by DNA Damage and Repair Pathway Profiling Analysis. Environ Sci Technol 52:6565-6575
Wang, Poguang; Giese, Roger W (2018) Interpretation of Mass Spectral Data for the Cisplatin 1,2 Intrastrand Guanine-Guanine Adduct. Chem Res Toxicol 31:1106-1107
Hojabri, Shirin; Rajic, Ljiljana; Alshawabkeh, Akram N (2018) Transient reactive transport model for physico-chemical transformation by electrochemical reactive barriers. J Hazard Mater 358:171-177
Ferguson, Kelly K; Kamai, Elizabeth M; Cantonwine, David E et al. (2018) Associations between repeated ultrasound measures of fetal growth and biomarkers of maternal oxidative stress and inflammation in pregnancy. Am J Reprod Immunol 80:e13017
Elkin, Elana R; Harris, Sean M; Loch-Caruso, Rita (2018) Trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line. Toxicol Appl Pharmacol 338:30-42

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