Health Disparities in Alcohol-related Risks for Injuries, Diabetes, and Cardiovascular Morbidity and Mortality The focus of this Center Project is on analyses of selected major causes of illness, injury, disability and death where significant racial/ethnic and socioeconomic disparities are evident in the US and which are substantially alcohol-related. Proposed analyses will extend prior and ongoing research programs led by PI Kerr and Dr. Cherpitel focusing on injuries and unintentional injury and motor vehicle crash subtypes which have high mortality rates in all racial/ethnic groups, particularly for those under age 40, and on diabetes, hypertension and heart problems, which are prevalent and inter-related diseases, conditions and causes of death with large racial/ethnic and socioeconomic disparities. Our goals are to provide the details of recent health disparities in these major alcohol-related causes and to analyze the roles of alcohol use patterns for these health risks to improve understanding of the role of alcohol and the potential for reducing morbidity, mortality and disparities through alcohol policy, prevention efforts and treatment. There has been very limited research on the potential roles of racial and ethnic differences in life-course drinking and alcohol-related problems in health disparities. Data sources are the Behavioral Risk Factor Surveillance System, the National Alcohol Surveys (NAS) and State-level mortality data from the National Center for Health Statistics. Analyses will primarily focus on Black and Latino groups as compared to a White reference group with NAS analyses also considering socioeconomic disparities and some mortality analyses also considering Asian and Pacific Islander and American Indian and Alaska Native groups. Mortality analyses will focus on major acute and chronic causes with significant racial/ethnic disparities and alcohol involvement: unintentional injuries and the subtype of motor vehicle crashes and cardiovascular-related areas of ischemic heart disease (IHD), hypertension and diabetes. The proposed study will evaluate risks for health outcomes among NAS respondents and will detail disparities in mortality rates and model relationships with sub-group drinking patterns from the BRFSS. Key innovations will include attention to life-course alcohol patterns in the NAS addressing the endogeniety of drinking and health and associations between alcohol patterns and other health risk behaviors, attention of beverage- specific associations in the NAS and consideration of state linked alcohol tax-based instrumental variable (IV) methods for causal effects. Alcohol tax measures are new estimates of spirits, wine and beer tax rates developed by PI Kerr that allow for the inclusion of spirits control states and ad valorem taxes in a framework where all tax rates are converted to equivalent wholesale-level beverage volume excise tax rates. This innovation improves the accuracy of tax rates allows the inclusion of 18 spirits control states providing greater variability over the period of analyses, which should significantly improve the performance of the IV models. Results will identify and quantify disparities in alcohol patterns and alcohol pattern risk relationships with morbidity and mortality, testing hypotheses regarding differential risks.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Specialized Center (P50)
Project #
5P50AA005595-39
Application #
9617182
Study Section
Special Emphasis Panel (ZAA1)
Project Start
Project End
Budget Start
2019-01-01
Budget End
2019-12-31
Support Year
39
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Public Health Institute
Department
Type
DUNS #
128663390
City
Oakland
State
CA
Country
United States
Zip Code
94607
Zemore, Sarah E; Mulia, Nina; Williams, Edwina et al. (2017) Job loss and alcohol dependence among Blacks and Whites in a National Longitudinal Survey. J Ethn Subst Abuse 16:314-327
Gilbert, Paul A; Drabble, Laurie; Daniel-Ulloa, Jason et al. (2017) Alcohol Outcomes by Sexual Orientation and Race/Ethnicity: Few Findings of Higher Risk. J Stud Alcohol Drugs 78:406-414
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Kerr, William C; Lui, Camillia; Ye, Yu (2017) Trends and age, period and cohort effects for marijuana use prevalence in the 1984-2015 US National Alcohol Surveys. Addiction :
Holguin, Fernando; Moughrabieh, M Anas; Ojeda, Victoria et al. (2017) Respiratory Health in Migrant Populations: A Crisis Overlooked. Ann Am Thorac Soc 14:153-159
Cherpitel, Cheryl J; Ye, Yu; Kerr, William C (2017) Risk of Past Year Injury Related to Hours of Exposure to an Elevated Blood Alcohol Concentration and Average Monthly Alcohol Volume: Data from 4 National Alcohol Surveys (2000 to 2015). Alcohol Clin Exp Res :
Finno-Velasquez, Megan; Palmer, Lindsey; Prindle, John et al. (2017) A birth cohort study of Asian and Pacific Islander children reported for abuse or neglect by maternal nativity and ethnic origin. Child Abuse Negl 72:54-65
Greenfield, Thomas K; Williams, Edwina; Kerr, William C et al. (2017) Washington State Spirits Privatization: How Satisfied were Liquor Purchasers Before and After, and by Type of Retail Store in 2014? Subst Use Misuse :1-7
MacLeod, Kara E; Karriker-Jaffe, Katherine J; Satariano, William A et al. (2017) Drinking and driving and perceptions of arrest risk among California drivers: Relationships with DUI arrests in their city of residence. Traffic Inj Prev 18:566-572
Karriker-Jaffe, Katherine J; Greenfield, Thomas K; Kaplan, Lauren M (2017) Distress and alcohol-related harms from intimates, friends, and strangers. J Subst Use 22:434-441

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