Health Disparities in Alcohol-related Risks for Injuries, Diabetes, and Cardiovascular Morbidity and Mortality The focus of this Center Project is on analyses of selected major causes of illness, injury, disability and death where significant racial/ethnic and socioeconomic disparities are evident in the US and which are substantially alcohol-related. Proposed analyses will extend prior and ongoing research programs led by PI Kerr and Dr. Cherpitel focusing on injuries and unintentional injury and motor vehicle crash subtypes which have high mortality rates in all racial/ethnic groups, particularly for those under age 40, and on diabetes, hypertension and heart problems, which are prevalent and inter-related diseases, conditions and causes of death with large racial/ethnic and socioeconomic disparities. Our goals are to provide the details of recent health disparities in these major alcohol-related causes and to analyze the roles of alcohol use patterns for these health risks to improve understanding of the role of alcohol and the potential for reducing morbidity, mortality and disparities through alcohol policy, prevention efforts and treatment. There has been very limited research on the potential roles of racial and ethnic differences in life-course drinking and alcohol-related problems in health disparities. Data sources are the Behavioral Risk Factor Surveillance System, the National Alcohol Surveys (NAS) and State-level mortality data from the National Center for Health Statistics. Analyses will primarily focus on Black and Latino groups as compared to a White reference group with NAS analyses also considering socioeconomic disparities and some mortality analyses also considering Asian and Pacific Islander and American Indian and Alaska Native groups. Mortality analyses will focus on major acute and chronic causes with significant racial/ethnic disparities and alcohol involvement: unintentional injuries and the subtype of motor vehicle crashes and cardiovascular-related areas of ischemic heart disease (IHD), hypertension and diabetes. The proposed study will evaluate risks for health outcomes among NAS respondents and will detail disparities in mortality rates and model relationships with sub-group drinking patterns from the BRFSS. Key innovations will include attention to life-course alcohol patterns in the NAS addressing the endogeniety of drinking and health and associations between alcohol patterns and other health risk behaviors, attention of beverage- specific associations in the NAS and consideration of state linked alcohol tax-based instrumental variable (IV) methods for causal effects. Alcohol tax measures are new estimates of spirits, wine and beer tax rates developed by PI Kerr that allow for the inclusion of spirits control states and ad valorem taxes in a framework where all tax rates are converted to equivalent wholesale-level beverage volume excise tax rates. This innovation improves the accuracy of tax rates allows the inclusion of 18 spirits control states providing greater variability over the period of analyses, which should significantly improve the performance of the IV models. Results will identify and quantify disparities in alcohol patterns and alcohol pattern risk relationships with morbidity and mortality, testing hypotheses regarding differential risks.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Specialized Center (P50)
Project #
5P50AA005595-39
Application #
9617182
Study Section
Special Emphasis Panel (ZAA1)
Project Start
Project End
Budget Start
2019-01-01
Budget End
2019-12-31
Support Year
39
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Public Health Institute
Department
Type
DUNS #
128663390
City
Oakland
State
CA
Country
United States
Zip Code
94607
Karriker-Jaffe, Katherine J; Witbrodt, Jane; Subbaraman, Meenakshi S et al. (2018) What Happens After Treatment? Long-Term Effects of Continued Substance Use, Psychiatric Problems and Help-Seeking on Social Status of Alcohol-Dependent Individuals. Alcohol Alcohol 53:394-402
Kerr, William C; Ye, Yu; Williams, Edwina et al. (2018) Lifetime Alcohol Use Patterns and Risk of Diabetes Onset in the National Alcohol Survey. Alcohol Clin Exp Res :
Kerr, William C; Ye, Yu; Subbaraman, Meenakshi Sabina et al. (2018) Changes in Marijuana Use Across the 2012 Washington State Recreational Legalization: Is Retrospective Assessment of Use Before Legalization More Accurate? J Stud Alcohol Drugs 79:495-502
Borges, Guilherme; Zemore, Sarah E; Orozco, Ricardo et al. (2018) Drug use on both sides of the US-Mexico border. Salud Publica Mex 60:451-461
Karriker-Jaffe, Katherine J; Greenfield, Thomas K; Mulia, Nina et al. (2018) Ten-Year Trend in Women's Reasons for Abstaining or Limiting Drinking: The 2000 and 2010 United States National Alcohol Surveys. J Womens Health (Larchmt) 27:665-675
Bensley, Kara M; Seelig, Amber D; Armenta, Richard F et al. (2018) Posttraumatic Stress Disorder Symptom Association With Subsequent Risky and Problem Drinking Initiation. J Addict Med 12:353-362
Kerr, William C; Lui, Camillia; Ye, Yu (2018) Trends and age, period and cohort effects for marijuana use prevalence in the 1984-2015 US National Alcohol Surveys. Addiction 113:473-481
Karriker-Jaffe, Katherine J; Li, Libo; Greenfield, Thomas K (2018) Estimating mental health impacts of alcohol's harms from other drinkers: using propensity scoring methods with national cross-sectional data from the United States. Addiction 113:1826-1839
Trangenstein, Pamela J; Morojele, Neo K; Lombard, Carl et al. (2018) Heavy drinking and contextual risk factors among adults in South Africa: findings from the International Alcohol Control study. Subst Abuse Treat Prev Policy 13:43
Klinger, Jamie L; Karriker-Jaffe, Katherine J; Witbrodt, Jane et al. (2018) Effects of Distance to Treatment on Subsequent Alcohol Consumption. Drugs (Abingdon Engl) 25:173-180

Showing the most recent 10 out of 257 publications