Abstract

The primary function of the animal core is provide animals trained either in an ethanol-water discrimination task or to self-administer ethanol. These two animal models form the basis upon which the Center will approach the Specific Research Aims. Drs. Grant and Samson will oversee this core, with two full time technicians responsible for daily operation. The primary value of the core, besides reducing the total cost of animal preparation, is the ability to provide uniform training of the animals to all Center projects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Specialized Center (P50)
Project #
5P50AA011997-02
Application #
6299189
Study Section
Project Start
2000-01-01
Project End
2000-12-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
2
Fiscal Year
2000
Total Cost
$323,494
Indirect Cost

  Institution

Name
Wake Forest University Health Sciences
Department
Type
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106

  Publications

Davenport, April T; Grant, Kathleen A; Szeliga, Kendall T et al. (2014) Standardized method for the harvest of nonhuman primate tissue optimized for multiple modes of analyses. Cell Tissue Bank 15:99-110
Freeman, Willard M; Vanguilder, Heather D; Guidone, Elizabeth et al. (2011) Plasma proteomic alterations in non-human primates and humans after chronic alcohol self-administration. Int J Neuropsychopharmacol 14:899-911
Lyn, Heidi; Pierre, Peter; Bennett, Allyson J et al. (2011) Planum temporale grey matter asymmetries in chimpanzees (Pan troglodytes), vervet (Chlorocebus aethiops sabaeus), rhesus (Macaca mulatta) and bonnet (Macaca radiata) monkeys. Neuropsychologia 49:2004-12
Graef, John D; Godwin, Dwayne W (2010) Intrinsic plasticity in acquired epilepsy: too much of a good thing? Neuroscientist 16:487-95
Freeman, Willard M; Salzberg, Anna C; Gonzales, Steven W et al. (2010) Classification of alcohol abuse by plasma protein biomarkers. Biol Psychiatry 68:219-22
Cheng, Heng-Jie; Grant, Kathleen A; Han, Qing-Hua et al. (2010) Up-regulation and functional effect of cardiac ?3-adrenoreceptors in alcoholic monkeys. Alcohol Clin Exp Res 34:1171-81
McCauley, Anita K; Frank, Steven T; Godwin, Dwayne W (2009) Brainstem nitrergic innervation of the mouse visual thalamus. Brain Res 1278:34-49
Shively, Carol A; Mietus, Joseph E; Grant, Kathleen A et al. (2007) Effects of chronic moderate alcohol consumption and novel environment on heart rate variability in primates (Macaca fascicularis). Psychopharmacology (Berl) 192:183-91
Walker, Stephen J; Wang, Yulei; Grant, Kathleen A et al. (2006) Long versus short oligonucleotide microarrays for the study of gene expression in nonhuman primates. J Neurosci Methods 152:179-89
Freeman, Willard M; Gooch, Randy S; Lull, Melinda E et al. (2006) Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration. Alcohol Alcohol 41:300-5

Showing the most recent 10 out of 33 publications