The Administrative Core provides the organization and structure for planning and implementation of ADRC core and research activities. The core supervises all ADRC functions and the Clinical, Data Management &Statistics, Neuropathology &Genetics, Education &Information, and Neuroimaging Cores. The Administrative Core monitors ADRC budgets to ensure fiscal responsibility;organizes the review and funding process for pilot studies, and monitors ADRC research projects, pilot projects and studies utilizing ADRC subjects or resources. This core determines new research directions, including the recruitment of new investigators to work in AD. Establishment and expansion of outreach efforts to the medically underserved and minority communities are directed and stimulated by the Core. The Core also oversees participation in multicenter studies, data transfer to the NACC and other NIA data repositories, tissue and DNA samples to NIA repositories, cross-ADC collaborations, and other national and international initiatives. Through the establishment of a comprehensive communications system including Website and e-mail ListServes, the Core Directors, project investigators, and staff will maintain an integrated, coherent and multidisciplinary focus. The goals of the Administrative Core are achieved by the Executive Committee, which is comprised of the Director, Co-Director, Associate Director, Center Administrator, and Core and Project Leaders. It is aided in these tasks by advice of the Internal and External Advisory Committees, and input is solicited from our investigators. The Internal Advisory Committee meets once per year, is chaired by the Senior Vice Chancellor/Dean of the Medical School, and includes the former Senior Vice Chancellor for the Health Sciences, the Chair of Psychiatry, the former Chair of Epidemiology at the University of Pittsburgh and the Co-Director of the Center for the Neural Basis of Cognition. They provide guidance on policy, administration, and scientific direction. The External Advisory Board is comprised of nationally respected researchers and clinicians with expertise in disciplines relevant to AD. They provide scientific critiques of research and operations of the ADRC as well as recommendations for new initiatives.

Public Health Relevance

The successful operation of this Core will advance research in AD and other dementias by facilitating the interface between basic and clinical researchers, assuring the development of collaborations among investigators, developing pilot projects to foster new research, and bringing new investigators to the field.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Pittsburgh
United States
Zip Code
Mez, Jesse; Chung, Jaeyoon; Jun, Gyungah et al. (2017) Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement 13:119-129
Montgomery, Valencia; Harris, Katie; Stabler, Anthony et al. (2017) Effects of Delay Duration on the WMS Logical Memory Performance of Older Adults with Probable Alzheimer's Disease, Probable Vascular Dementia, and Normal Cognition. Arch Clin Neuropsychol 32:375-380
Diniz, Breno S; Teixeira, Antonio L; Cao, Fei et al. (2017) History of Bipolar Disorder and the Risk of Dementia: A Systematic Review and Meta-Analysis. Am J Geriatr Psychiatry 25:357-362
Weintraub, Sandra; Besser, Lilah; Dodge, Hiroko H et al. (2017) Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord :
Grill, Joshua D; Apostolova, Liana G; Bullain, Szofia et al. (2017) Communicating mild cognitive impairment diagnoses with and without amyloid imaging. Alzheimers Res Ther 9:35
Brenowitz, Willa D; Keene, C Dirk; Hawes, Stephen E et al. (2017) Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples. Neurobiol Aging 53:83-92
Katsumata, Yuriko; Nelson, Peter T; Ellingson, Sally R et al. (2017) Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2. Neurobiol Aging 53:193.e17-193.e25
Ombrello, Michael J; Arthur, Victoria L; Remmers, Elaine F et al. (2017) Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications. Ann Rheum Dis 76:906-913
Stillman, Chelsea M; Lopez, Oscar L; Becker, James T et al. (2017) Physical activity predicts reduced plasma ? amyloid in the Cardiovascular Health Study. Ann Clin Transl Neurol 4:284-291
Moga, Daniela C; Abner, Erin L; Wu, Qishan et al. (2017) Bladder antimuscarinics and cognitive decline in elderly patients. Alzheimers Dement (N Y) 3:139-148

Showing the most recent 10 out of 592 publications