Abstract

The role of the Data Management and Statistics Core will be to facilitate research through the University of Pittsburgh Alzheimer's Disease Research Center by providing high quality data management and study methodologic support. Specifically, the aims of this Core will be: 1. Provide efficient database management systems to ensure complete and accurate research data 2. Collaborate with NACC and NIA initiatives to contribute to national databases 3. Provide computerized systems to support processes integral to the operations of the ADRC 4. Provide methodological and analytical support to ADRC researchers.

Public Health Relevance

The data collected in the various projects and Cores of the ADRC require central management to maximize their utility for scientific investigations. A Core with personnel having the expertise to effectively and efficiently create complete and accurate computerized databases is essential to the scientific mission of the ADRC, including the ability to share data with approved investigators locally, nationally, and internationally.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005133-30
Application #
8449127
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
30
Fiscal Year
2013
Total Cost
$155,937
Indirect Cost
$52,451

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Lancour, Daniel; Naj, Adam; Mayeux, Richard et al. (2018) One for all and all for One: Improving replication of genetic studies through network diffusion. PLoS Genet 14:e1007306
Tudorascu, Dana L; Minhas, Davneet S; Lao, Patrick J et al. (2018) The use of Centiloids for applying [11C]PiB classification cutoffs across region-of-interest delineation methods. Alzheimers Dement (Amst) 10:332-339
DeKosky, Steven T; Jaffee, Michael; Bauer, Russell (2018) Long-term Mortality in NFL Professional Football Players: No Significant Increase, but Questions Remain. JAMA 319:773-775
Davis, Jeremy J (2018) Performance validity in older adults: Observed versus predicted false positive rates in relation to number of tests administered. J Clin Exp Neuropsychol 40:1013-1021
Burke, Shanna L; Maramaldi, Peter; Cadet, Tamara et al. (2018) Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E. Int J Geriatr Psychiatry 33:200-211
Snitz, Beth E; Wang, Tianxiu; Cloonan, Yona Keich et al. (2018) Risk of progression from subjective cognitive decline to mild cognitive impairment: The role of study setting. Alzheimers Dement 14:734-742
Qian, Winnie; Fischer, Corinne E; Schweizer, Tom A et al. (2018) Association Between Psychosis Phenotype and APOE Genotype on the Clinical Profiles of Alzheimer's Disease. Curr Alzheimer Res 15:187-194
Fowler, Nicole R; Shaaban, C Elizabeth; Torke, Alexia M et al. (2018) ""I'm Not Sure We Had A Choice"": Decision Quality and The Use of Cardiac Implantable Electronic Devices In Older Adults With Cognitive Impairment. Cardiol Cardiovasc Med 2:10-26
Gallagher, Damien; Kiss, Alex; Lanctot, Krista et al. (2018) Depression and Risk of Alzheimer Dementia: A Longitudinal Analysis to Determine Predictors of Increased Risk among Older Adults with Depression. Am J Geriatr Psychiatry 26:819-827
Lin, Ming; Gong, Pinghua; Yang, Tao et al. (2018) Big Data Analytical Approaches to the NACC Dataset: Aiding Preclinical Trial Enrichment. Alzheimer Dis Assoc Disord 32:18-27

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