The Pacific Northwest Dementia and Aging (PANDA) Neuropathology (NP) Group is a successful cooperative effort between the Alzheimer's Disease (AD) Center at Oregon Health &Science University (OHSU) and the AD Research Center (ADRC) at the University of Washington (UW) that was initiated in July 2003. The initial four Specific Aims of the PANDA NP Group are unchanged from our previous applications: (i) provide diagnostic expertise, (ii) facilitate research, (iii) teach and mentor trainees, and (iv) develop innovative approaches. Two new Specific Aims have been added in this application that are focused on Targeted Molecular Testing (TMT): (v) quantify targeted cerebrospinal fluid (CSF) biomarkers in the UW ADRC CSF Bank that derives in large part from the OHSU ADC and UW ADRC Clinical Cores, and (vi) provide targeted genetic testing relevant to AD and related neurodegenerative diseases. All of our activities are focused on enhancing the research value of tissue and body fluid donations from cognitively healthy individuals and patients with neurodegenerative diseases while insuring proper safeguards.

Public Health Relevance

AD is a looming public health disaster for US citizens, both patients and caregivers, and our health care system. There Is no effective treatment for AD. This application is a response to the need to deepen our understanding of AD so effective treatments can be developed.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005136-30
Application #
8459480
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
30
Fiscal Year
2013
Total Cost
$489,915
Indirect Cost
$161,112
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
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