The USC ADRC focuses on reducing Alzheimer and vascular contributions to cognitive Impairment in diverse populations. Personnel of the Data Management and Statistics core provide particular expertise and collaborative experience in relation to overall ADRC objectives. The USC ADRC Data Management and Statistics Core collaborates with Administrative, Clinical, Pathology, Neuroimaging and Education Cores to provide database design, data collection and data management services. Biostatistical services include consultation with core directors, project directors, pilot study investigators and participating ADRC investigators regarding study designs, development of data sets and analytic plans, as well as direct analysis of ADRC-related data. Data management services include database systems design and maintenance, data entry and management of UDS, NACC Neuropathology, and other ADRC data, and interactions with NACC on issues related to data systems, uploading and retrieval of data, and responses to data queries. The overall objective of the Data Management and Statistics Core is to provide high quality data management and statistical consulting to the research projects and the cores of the ADRC, as accomplished by the following aims: 1. To maintain a Web-based data management system. 2. To train and work with staff of the Administrative, Clinical, Pathology, and Education Cores to ensure timely and accurate data entry and management 3. To work with the NACC to provide timely and complete submission of local UDS and Neuropathology data. 4. To provide data reports to core staff and investigators on a routine and as needed basis. 5. To provide biostatistical consulting to individual ADRC investigators in the design, coordination, and analyses of ADRC-related projects, including pilot projects.

Public Health Relevance

The Data Management and Statistics Core provides consulting on and provision of data coordination and biostatistical services to promote and optimize the research of the USC ADRC. Provision of accurate and reliable database support, development of valid study designs, and appropriate analysis of resulting data are fundamental to the completion of valid research.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Southern California
Los Angeles
United States
Zip Code
Sano, Mary; Zhu, Carolyn W; Grossman, Hillel et al. (2017) Longitudinal Cognitive Profiles in Diabetes: Results From the National Alzheimer's Coordinating Center's Uniform Data. J Am Geriatr Soc 65:2198-2204
Tripodis, Yorghos; Alosco, Michael L; Zirogiannis, Nikolaos et al. (2017) The Effect of Traumatic Brain Injury History with Loss of Consciousness on Rate of Cognitive Decline Among Older Adults with Normal Cognition and Alzheimer's Disease Dementia. J Alzheimers Dis 59:251-263
Brenowitz, Willa D; Hubbard, Rebecca A; Keene, C Dirk et al. (2017) Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample. Alzheimers Dement 13:654-662
Jutkowitz, Eric; Kane, Robert L; Gaugler, Joseph E et al. (2017) Societal and Family Lifetime Cost of Dementia: Implications for Policy. J Am Geriatr Soc 65:2169-2175
Lao, Yi; Nguyen, Binh; Tsao, Sinchai et al. (2017) A T1 and DTI fused 3D corpus callosum analysis in MCI subjects with high and low cardiovascular risk profile. Neuroimage Clin 14:298-307
Moheb, Negar; Mendez, Mario F; Kremen, Sarah A et al. (2017) Executive Dysfunction and Behavioral Symptoms Are Associated with Deficits in Instrumental Activities of Daily Living in Frontotemporal Dementia. Dement Geriatr Cogn Disord 43:89-99
Gahm, Jin Kyu; Shi, Yonggang (2017) Holistic Mapping of Striatum Surfaces in the Laplace-Beltrami Embedding Space. Med Image Comput Comput Assist Interv 10433:21-30
Woodward, Nicholas C; Pakbin, Payam; Saffari, Arian et al. (2017) Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for CA1 neurons. Neurobiol Aging 53:48-58
Tang, Yuchun; Sun, Wei; Toga, Arthur W et al. (2017) A probabilistic atlas of human brainstem pathways based on connectome imaging data. Neuroimage 169:227-239
Monsell, Sarah E; Mock, Charles; Fardo, David W et al. (2017) Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology. Alzheimer Dis Assoc Disord 31:232-238

Showing the most recent 10 out of 503 publications