The objectives ofthe Columbia University Education and Information Core are: to provide training to physicians about Alzheimer's disease;to facilitate the recruitment and retention of research participants;to develop innovative and culturally sensitive outreach programs to educate the community and promote ADRC activities;and to complement and support the initiatives of the Clinical Core, the Neuropathology Core and the Genetics Core. To meet these objectives, we will build upon our past successes to expand our reach and impact. Over the next 5 years, the Education Core will continue our comprehensive education program for physicians-in-training with lectures and outpatient electives. We will continue to design and implement seminars, presentations, publications, and CME courses to familiarize clinicians with standard of care and research trends in the diagnosis, treatment, and management of dementia. The Education Core will continue our service-specific activities of providing education to caregivers and the lay public about disease treatment and research opportunities. We will continue to design educational programs for the community using culturally sensitive information, presentations and materials, with a specific focus on addressing participation in clinical trials and obtaining permission for brain autopsy. Using our highly successful African American outreach program as a model, we will expand outreach to the Hispanic community to include community presentations and outreach to Latino physicians. We will meet our service-specific aim of facilitating recruitment into the genetics initiative by designing educational programs targeted to minorities. New programs will be designed to assist the Clinical Core in obtaining permission for lumbar puncture for CSF biomarkers. We will expand our services to include an early stage caregiver support group and educational workshop series. We will continue and develop the evaluation of our programs to ensure that they meet the educational objectives and goals.

Public Health Relevance

Alzheimers disease affects more than 5 million people but still remains underdiagnosed and undertreated. Education of the lay public and physicians is necessary to increase awareness about the disease.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Specialized Center (P50)
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Special Emphasis Panel (ZAG1-ZIJ-4)
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Columbia University
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Vardarajan, Badri N; Zhang, Yalun; Lee, Joseph H et al. (2015) Coding mutations in SORL1 and Alzheimer disease. Ann Neurol 77:215-27
Mecozzi, Vincent J; Berman, Diego E; Simoes, Sabrina et al. (2014) Pharmacological chaperones stabilize retromer to limit APP processing. Nat Chem Biol 10:443-9
Pan, Jie J; Lee, Michelle; Honig, Lawrence S et al. (2014) Alzheimer's-related changes in non-demented essential tremor patients vs. controls: links between tau and tremor? Parkinsonism Relat Disord 20:655-8
Baleriola, Jimena; Walker, Chandler A; Jean, Ying Y et al. (2014) Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions. Cell 158:1159-72
Pelton, Gregory H; Andrews, Howard; Roose, Steven P et al. (2014) Donepezil treatment of older adults with cognitive impairment and depression (DOTCODE study): clinical rationale and design. Contemp Clin Trials 37:200-8
Sproul, Andrew A; Jacob, Samson; Pre, Deborah et al. (2014) Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors. PLoS One 9:e84547
Khan, Usman A; Liu, Li; Provenzano, Frank A et al. (2014) Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease. Nat Neurosci 17:304-11
Salloway, Stephen; Sperling, Reisa; Fox, Nick C et al. (2014) Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med 370:322-33
Choi, Ben Jiwon; Imlach, Wendy L; Jiao, Wei et al. (2014) Miniature neurotransmission regulates Drosophila synaptic structural maturation. Neuron 82:618-34
Salm, Melissa; Abbate, Kristopher; Appelbaum, Paul et al. (2014) Use of genetic tests among neurologists and psychiatrists: knowledge, attitudes, behaviors, and needs for training. J Genet Couns 23:156-63

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